Literature DB >> 2863363

Characterization of enhanced intestinal permeability; electrophysiological study on the effects of diclofenac and ethylenediaminetetraacetic acid.

S Yamashita, H Saitoh, K Nakanishi, M Masada, T Nadai, T Kimura.   

Abstract

The mechanism of the enhancing effects of diclofenac sodium and disodium ethylenediaminetetraacetate (EDTA) on intestinal permeability to sulphanilic acid were investigated in the rat isolated jejunum by an electrophysiological technique. The results suggested that diclofenac sodium increased the mucosal-to-serosal flux rate of sulphanilic acid by enhancing both transcellular and paracellular permeabilities while the effect of EDTA was located only in the paracellular pathway.

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Year:  1985        PMID： 2863363     DOI： 10.1111/j.2042-7158.1985.tb03056.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  3 in total

1.  Differences in the enhancing effects of sodium caprate on colonic and jejunal drug absorption.

Authors:  M Tomita; T Sawada; T Ogawa; H Ouchi; M Hayashi; S Awazu
Journal:  Pharm Res       Date:  1992-05       Impact factor: 4.200

2.  Simultaneous in vitro measurement of intestinal tissue permeability and transepithelial electrical resistance (TEER) using Sweetana-Grass diffusion cells.

Authors:  S C Sutton; A E Forbes; R Cargill; J H Hochman; E L LeCluyse
Journal:  Pharm Res       Date:  1992-03       Impact factor: 4.200

Review 3.  Examples of Inverse Comorbidity between Cancer and Neurodegenerative Diseases: A Possible Role for Noncoding RNA.

Authors:  Michele Salemi; Maria Paola Mogavero; Giuseppe Lanza; Laura M Mongioì; Aldo E Calogero; Raffaele Ferri
Journal:  Cells       Date:  2022-06-15       Impact factor: 7.666
  3 in total

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