Literature DB >> 28632519

Age is the Most Significantly Associated Risk Factor With the Development of Delirium in Patients Hospitalized for More Than Five Days in Surgical Wards: Retrospective Cohort Study.

Keisuke Kubota1, Akihiro Suzuki1, Sachiko Ohde2, Ui Yamada3, Takashi Hosaka4, Fumiko Okuno5, Ikumi Fujitani6, Aya Koitabashi6, Gen Shimada1,7, Akihiro Kishida1.   

Abstract

OBJECTIVE: The primary purpose of this study was to assess risk factors for delirium in patients staying in a surgical ward for more than 5 days. The secondary purpose was to assess outcomes in patients with delirium.
BACKGROUND: Delirium is a syndrome characterized by acute fluctuations in mental status. Patients with delirium are at increased risk of adverse inpatient events, higher mortality and morbidity rates, prolonged hospital stays, and increased health care costs.
METHODS: Participants in this study were 2168 patients who had been admitted to the surgical ward of St. Luke's International Hospital for 5 days or more between January 2011 and December 2014. Data on these patients were collected retrospectively from hospital medical records. Firstly, univariate and multivariate analyses were conducted to identify risk factors for delirium. Secondly, morbidity and mortality associated with delirium were analyzed.
RESULTS: Delirium occurred in 205 of 2168 patients (9.5%). Age, physical restraint, past history of a cerebrovascular disorder, malignancy, intensive care unit stay, pain, and high blood urea nitrogen value were significant risk factors for delirium in the multivariate analysis. Among these, age was the strongest factor, with an odds ratio for delirium of 12.953 in patients 75 years of age or older. The length of hospital stays and the mortality rates were higher in patients with delirium.
CONCLUSIONS: Results showed that age, and also physical restraint, past history of cerebrovascular disorder, malignancy, intensive care unit stay, pain, and high serum blood urea nitrogen were important factors associated with delirium in patients hospitalized for more than 5 days in a surgical ward.

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Mesh:

Year:  2018        PMID: 28632519     DOI: 10.1097/SLA.0000000000002347

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  10 in total

1.  Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women.

Authors:  Guo-Wen Lu; Yi-Er Chou; Wan-Ling Jin; Xiao-Bao Su
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2.  Risk factors of postoperative delirium in the knee and hip replacement patients: a systematic review and meta-analysis.

Authors:  Xiao Rong; Zi-Chuan Ding; Hao-da Yu; Shun-Yu Yao; Zong-Ke Zhou
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Authors:  Hanyi Li; Shunchang Han; Juan Feng
Journal:  Parkinsons Dis       Date:  2021-02-01

4.  Incidence and risk factors of delirium after percutaneous coronary intervention in individuals hospitalised for acute myocardial infarction: protocol for a systematic review and meta-analysis.

Authors:  Kaizhuang Huang; Jiaying Lu; Yaoli Zhu; Tao Cheng; Dahao Du; Xueqin Qian; Haiyan Pan; Xiaohua Wang; Hong Yang; Shaofei Lou
Journal:  BMJ Open       Date:  2020-12-30       Impact factor: 2.692

5.  Risk factors for delirium among SARS-CoV-2 positive veterans.

Authors:  Charles J Santos; Nebil Nuradin; Christopher Joplin; Alexandra E Leigh; Rebecca V Burke; Robin Rome; Jonathan McCall; Amanda M Raines
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6.  Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit.

Authors:  Zuli Fu; Qian Xu; Chiyuan Zhang; Hui Bai; Xuliang Chen; Yanfeng Zhang; Wanjun Luo; Guoqiang Lin
Journal:  Int J Gen Med       Date:  2021-09-21

7.  Lower preoperative serum uric acid level may be a risk factor for postoperative delirium in older patients undergoing hip fracture surgery: a matched retrospective case-control study.

Authors:  Lin Xu; Wenyuan Lyu; Penghui Wei; Qiang Zheng; Chengwei Li; Zheng Zhang; Jianjun Li
Journal:  BMC Anesthesiol       Date:  2022-09-07       Impact factor: 2.376

8.  Cognitive prehabilitation for geriatric patients undergoing elective surgery: a PRISMA-P-compliant protocol for a systematic review.

Authors:  Yu He; Wenchen Zou; Xiaochai Han; Caitao Chen; Anren Zhang; Nianyi Sun
Journal:  BMJ Open       Date:  2022-07-07       Impact factor: 3.006

9.  Incidence, risk factors, and cumulative risk of delirium among ICU patients: A case-control study.

Authors:  Yanbin Pan; Jianlong Yan; Zhixia Jiang; Jianying Luo; Jingjing Zhang; Kaihan Yang
Journal:  Int J Nurs Sci       Date:  2019-06-02

10.  Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.

Authors:  Jie Zhang; Bin Xiao; Chen-Xu Li; Yi Wang
Journal:  Neural Regen Res       Date:  2020-07       Impact factor: 5.135

  10 in total

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