| Literature DB >> 2863055 |
Abstract
Cyclic AMP (cAMP) levels were measured in both isolated and attached osteoclasts. The level of cAMP was 0.1 pmol/10(5) osteoclasts. No change in cAMP level of osteoclasts could be detected following calcitonin treatment. Parathyroid hormone (PTH) and prostaglandin E2 (PGE2) treatment stimulated cAMP production in proportion to alkaline phosphatase levels and divergent to acid phosphatase levels. This indicates that osteoblasts, not osteoclasts, were responsive to PTH and PGE2.Entities:
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Year: 1985 PMID: 2863055 DOI: 10.1016/0300-9629(85)91043-6
Source DB: PubMed Journal: Comp Biochem Physiol A Comp Physiol ISSN: 0300-9629