| Literature DB >> 28630196 |
Helio S Sader1, Rodrigo E Mendes2, Jennifer M Streit2, Robert K Flamm2.
Abstract
We evaluated trends in Staphylococcus aureus antimicrobial susceptibility in U.S. hospitals in the 2010-2016 period. A total of 21,056 clinical isolates from 42 medical centers were tested for susceptibility by broth microdilution methods. Methicillin-resistant S. aureus (MRSA) rates decreased from 50.0% (in 2010) to 42.2% (in 2016). Susceptibility to erythromycin, levofloxacin, and clindamycin increased slightly, whereas susceptibility to ceftaroline, trimethoprim-sulfamethoxazole, and tetracycline remained stable. Ceftaroline retained potent activity against methicillin-susceptible S. aureus (MSSA) and MRSA (97.2% susceptible) with no marked variations.Entities:
Keywords: MRSA; ceftaroline; cephalosporin; methicillin-resistant Staphylococcus aureus; skin and skin structure infection
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Year: 2017 PMID: 28630196 PMCID: PMC5571371 DOI: 10.1128/AAC.01043-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191