Mateusz K Hołda1, Mateusz Koziej2, Karolina Wszołek2, Wiesław Pawlik3, Agata Krawczyk-Ożóg4, Danuta Sorysz4, Piotr Łoboda3, Katarzyna Kuźma3, Marcin Kuniewicz5, Jacek Lelakowski6, Dariusz Dudek4, Wiesława Klimek-Piotrowska2. 1. Department of Anatomy, Jagiellonian University Medical College, Cracow, Poland; HEART - Heart Embryology and Anatomy Research Team, Jagiellonian University Medical College, Cracow, Poland. Electronic address: mkh@onet.eu. 2. Department of Anatomy, Jagiellonian University Medical College, Cracow, Poland; HEART - Heart Embryology and Anatomy Research Team, Jagiellonian University Medical College, Cracow, Poland. 3. Radiology Unit, Department of Allergy and Immunology, University Hospital, Jagiellonian University Medical College, Cracow, Poland. 4. Department of Interventional Cardiology, University Hospital, Jagiellonian University Medical College, Cracow, Poland. 5. Department of Anatomy, Jagiellonian University Medical College, Cracow, Poland; Department of Electrocardiology, Institute of Cardiology, The John Paul II Hospital in Cracow, Jagiellonian University Medical College, Cracow, Poland. 6. Department of Electrocardiology, Institute of Cardiology, The John Paul II Hospital in Cracow, Jagiellonian University Medical College, Cracow, Poland.
Abstract
BACKGROUND: The aim of this study is to provide a morphometric description of the left-sided septal pouch (LSSP), left atrial accessory appendages, and diverticula using cardiac multi-slice computed tomography (MSCT) and to compare results between patient subgroups. METHODS: Two hundred and ninety four patients (42.9% females) with a mean of 69.4±13.1years of age were investigated using MSCT. The presence of the LSSP, left atrial accessory appendages, and diverticula was evaluated. Multiple logistic regression analysis was performed to check whether the presence of additional left atrial structures is associated with increased risk of atrial fibrillation and cerebrovascular accidents. RESULTS: At least one additional left atrial structure was present in 51.7% of patients. A single LSSP, left atrial diverticulum, and accessory appendage were present in 35.7%, 16.0%, and 4.1% of patients, respectively. After adjusting for other risk factors via multiple logistic regression, patients with LSSP are more likely to have atrial fibrillation (OR=2.00, 95% CI=1.14-3.48, p=0.01). The presence of a LSSP was found to be associated with an increased risk of transient ischemic attack using multiple logistic regression analysis after adjustment for other risk factors (OR=3.88, 95% CI=1.10-13.69, p=0.03). CONCLUSIONS: In conclusion LSSPs, accessory appendages, and diverticula are highly prevalent anatomic structures within the left atrium, which could be easily identified by MSCT. The presence of LSSP is associated with increased risk for atrial fibrillation and transient ischemic attack.
BACKGROUND: The aim of this study is to provide a morphometric description of the left-sided septal pouch (LSSP), left atrial accessory appendages, and diverticula using cardiac multi-slice computed tomography (MSCT) and to compare results between patient subgroups. METHODS: Two hundred and ninety four patients (42.9% females) with a mean of 69.4±13.1years of age were investigated using MSCT. The presence of the LSSP, left atrial accessory appendages, and diverticula was evaluated. Multiple logistic regression analysis was performed to check whether the presence of additional left atrial structures is associated with increased risk of atrial fibrillation and cerebrovascular accidents. RESULTS: At least one additional left atrial structure was present in 51.7% of patients. A single LSSP, left atrial diverticulum, and accessory appendage were present in 35.7%, 16.0%, and 4.1% of patients, respectively. After adjusting for other risk factors via multiple logistic regression, patients with LSSP are more likely to have atrial fibrillation (OR=2.00, 95% CI=1.14-3.48, p=0.01). The presence of a LSSP was found to be associated with an increased risk of transient ischemic attack using multiple logistic regression analysis after adjustment for other risk factors (OR=3.88, 95% CI=1.10-13.69, p=0.03). CONCLUSIONS: In conclusion LSSPs, accessory appendages, and diverticula are highly prevalent anatomic structures within the left atrium, which could be easily identified by MSCT. The presence of LSSP is associated with increased risk for atrial fibrillation and transient ischemic attack.
Authors: Esmeralci Ferreira; Dinaldo Cavalcanti de Oliveira; Andressa Braga Barros; Valerio Fuks; Ângelo Antunes Salgado; Márcio José Montenegro da Costa; Sara Cristine Marques Dos Santos; Ivana Aragão; Márcia Bueno Castier; Luiz Kohn; Ricardo Mourilhe-Rocha; Felipe N Albuquerque; Roberto Esporcatte; Denilson Campos de Albuquerque Journal: Am J Case Rep Date: 2021-12-20