Literature DB >> 2862943

The effects of the combined administration of beta-adrenoceptor antagonists and non-steroidal anti-inflammatory drugs on ligation-induced arrhythmias in rats.

O Fagbemi.   

Abstract

Pretreatment of anaesthetized rats with intravenously administered beta-adrenoceptor antagonists or non-steroidal anti-inflammatory drugs (NSAIDs) reduced the incidence and severity of ventricular arrhythmia which resulted from acute coronary artery ligation. The beta-adrenoceptor antagonists preferentially suppressed the immediate (Phase 1A) arrhythmia while the NSAIDs suppressed the delayed (Phase 1B) arrhythmias. Combined administration of beta-adrenoceptor antagonists and the NSAIDs produced a more pronounced antiarrhythmic effect than either of the drugs alone.

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Year:  1985        PMID： 2862943      PMCID： PMC1916597          DOI： 10.1111/j.1476-5381.1985.tb08869.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  21 in total

1.  Effect of propranolol upon the hemoglobin-oxygen dissociation curve.

Authors:  R G Pendleton; D J Newman; S S Sherman; E G Brann; W E Maya
Journal:  J Pharmacol Exp Ther       Date:  1972-03       Impact factor: 4.030

2.  Protective effect of beta adrenoceptor blockade in experimental coronary occlusion in conscious dogs.

Authors:  M I Khan; J T Hamilton; G W Manning
Journal:  Am J Cardiol       Date:  1972-12       Impact factor: 2.778

3.  Reduction by propranolol of myocardial necrosis following temporary coronary artery occlusion in dogs.

Authors:  K A Reimer; M M Rasmussen; R B Jennings
Journal:  Circ Res       Date:  1973-09       Impact factor: 17.367

4.  Protection against epinephrine-induced myocardial necrosis by drugs that inhibit platelet aggregation.

Authors:  J I Haft; K Gershengorn; P D Kranz; R Oestreicher
Journal:  Am J Cardiol       Date:  1972-12       Impact factor: 2.778

5.  Aspirin selectively inhibits prostaglandin production in human platelets.

Authors:  J B Smith; A L Willis
Journal:  Nat New Biol       Date:  1971-06-23

6.  Early arrhythmias following experimental coronary occlusion in conscious dogs and their modification by beta-adrenoceptor blocking drugs.

Authors:  M I Khan; J T Hamilton; G W Manning
Journal:  Am Heart J       Date:  1973-09       Impact factor: 4.749

7.  Effect of catecholamines on platelet aggregation caused by thrombin.

Authors:  D P Thomas
Journal:  Nature       Date:  1967-07-15       Impact factor: 49.962

8.  Effect of propranolol on platelet function.

Authors:  B B Weksler; M Gillick; J Pink
Journal:  Blood       Date:  1977-02       Impact factor: 22.113

9.  The effect of aspirin, indomethacin and sodium meclofenamate on coronary artery ligation arrhythmias in anaesthetized rats.

Authors:  S O Fagbemi
Journal:  Eur J Pharmacol       Date:  1984-01-27       Impact factor: 4.432

10.  Effects of acetylsalicylic acid, dipyridamole, and hydrocortisone on epinephrine-induced myocardial injury in dogs.

Authors:  S Kraikitpanitch; C C Haygood; D J Baxter; A A Yunice; R D Lindeman
Journal:  Am Heart J       Date:  1976-11       Impact factor: 4.749
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  1 in total

1.  Use of non-steroidal anti-inflammatory drugs and risk of incident myocardial infarction and heart failure, and all-cause mortality in the Australian veteran community.

Authors:  Arduino A Mangoni; Richard J Woodman; Paraskevi Gaganis; Andrew L Gilbert; Kathleen M Knights
Journal:  Br J Clin Pharmacol       Date:  2010-06       Impact factor: 4.335
  1 in total

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