| Literature DB >> 28629073 |
Bianca Moldovan1, Luminita David2, Adriana Vulcu3, Liliana Olenic4, Maria Perde-Schrepler5, Eva Fischer-Fodor5, Ioana Baldea6, Simona Clichici6, Gabriela Adriana Filip6.
Abstract
A green, rapid and cost effective method for the bio-synthesis of silver nanoparticles (AgNPs), using polyphenols present in European cranberry bush fruit extracts was developed. The obtained AgNPs were characterized by ultra-violet visible spectroscopy (UV-VIS), Fourier transform - infrared spectroscopy (FT-IR), transmission electron microscopy (TEM) and X-ray diffraction patterns (XRD). The average size of the spherical AgNPs was found to be 25nm. The anti-inflammatory effect of the biomaterials was investigated, both in vitro (on HaCaT cell line, exposed to UVB radiation) and in vivo (on acute inflammation model in Wistar rats). Our results support the conclusion that the photosynthesized silver nanoparticles present a potent anti-inflammatory activity and could be successfully used as therapeutic tools for treatment of inflammation.Entities:
Keywords: Anti-inflammatory activity; Biosynthesis; Silver nanoparticles; Viburnum opulus L.
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Year: 2017 PMID： 28629073 DOI： 10.1016/j.msec.2017.05.122
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN： 0928-4931 Impact factor: 7.328