Literature DB >> 28628193

Modulation of epithelial cell polarity by bacterial pathogens.

Rocio Tapia1, Sarah E Kralicek1, Gail A Hecht1,2,3.   

Abstract

Epithelial cells constitute a physical barrier that aids in protecting the host from microbial pathogens. Polarized epithelial cells contain distinct apical and basolateral membrane domains separated by intercellular junctions, including tight junctions (TJs), which contribute to the maintenance of apical-basal polarity. Polarity complexes also contribute to the establishment of TJ formation. Several pathogens perturb epithelial TJ barrier function and structure in addition to causing a loss of apical-basal polarity. Here, we review the impact of pathogenic bacteria on the disruption of cell-cell junctions and epithelial polarity.
© 2017 New York Academy of Sciences.

Entities:  

Keywords:  EPEC; apical-basal polarity; enteropathogenic Escherichia coli; tight junctions

Mesh：

Substances：

Year:  2017        PMID： 28628193      PMCID： PMC5713485          DOI： 10.1111/nyas.13388

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  79 in total

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Authors:  Paul Dean; Brendan Kenny
Journal:  Mol Microbiol       Date:  2004-11       Impact factor: 3.501

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Journal:  Cell Microbiol       Date:  2008-04-21       Impact factor: 3.715

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Journal:  Cell       Date:  1990-03-09       Impact factor: 41.582

5.  The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection.

Authors:  Ajitha Thanabalasuriar; Jinoh Kim; Samantha Gruenheid
Journal:  Microbes Infect       Date:  2013-06-06       Impact factor: 2.700

6.  Mechanism of inhibition of Na+-glucose cotransport in the chronically inflamed rabbit ileum.

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Journal:  Gastroenterology       Date:  1990-07       Impact factor: 22.682

8.  CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells.

Authors:  Céline Lemmers; Didier Michel; Lydie Lane-Guermonprez; Marie-Hélène Delgrossi; Emmanuelle Médina; Jean-Pierre Arsanto; André Le Bivic
Journal:  Mol Biol Cell       Date:  2004-01-12       Impact factor: 4.138

9.  14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor.

Authors:  J Liao; M B Omary
Journal:  J Cell Biol       Date:  1996-04       Impact factor: 10.539

Review 10.  Tight junctions: molecular architecture and function.

Authors:  Saima Aijaz; Maria S Balda; Karl Matter
Journal:  Int Rev Cytol       Date:  2006
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  5 in total

1.  Reversal of Pathogen-Induced Barrier Defects in Intestinal Epithelial Cells by Contra-pathogenicity Agents.

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Review 2.  Recent advances in the therapeutic efficacy of hepatocyte growth factor gene-modified mesenchymal stem cells in multiple disease settings.

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Authors:  Emanuel Schulz; Michael Schumann; Martina Schneemann; Violaine Dony; Anja Fromm; Oliver Nagel; Jörg-Dieter Schulzke; Roland Bücker
Journal:  Toxins (Basel)       Date:  2021-07-26       Impact factor: 4.546

4.  Comparative proteomics analysis indicates that palmatine contributes to transepithelial migration by regulating cellular adhesion.

Authors:  Wang Hui; Yang Feng; Xin Ruihua; He Jiongjie; Cui Dongan; Sun Yan; Zhang Shidong
Journal:  Pharm Biol       Date:  2020-12       Impact factor: 3.503

5.  Disassembly of the apical junctional complex during the transmigration of Leptospira interrogans across polarized renal proximal tubule epithelial cells.

Authors:  Isabel Sebastián; Nobuhiko Okura; Bruno M Humbel; Jun Xu; Idam Hermawan; Chiaki Matsuura; Malgorzata Hall; Chitoshi Takayama; Tetsu Yamashiro; Shuichi Nakamura; Claudia Toma
Journal:  Cell Microbiol       Date:  2021-05-06       Impact factor: 3.715
  5 in total

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