Literature DB >> 28624313

Eplerenone, a new treatment for an old problem: Retinitis pigmentosa with recalcitrant macular edema.

R Campos Polo1, C Rubio Sánchez2, D M García Guisado2, M J Díaz Luque2.   

Abstract

CASE REPORT: The case involves a 35-year-old man, with a history of retinitis pigmentosa, who presented with a bilateral cystoid macular oedema associated with bilateral epiretinal membrane, which was resistant to treatment with oral acetazolamide and intravitreal bevacizumab. The treatment with oral eplerenone was able to improve the visual acuity and macular thickness of this patient. DISCUSSION: A variety of treatments have been proposed for the management of cystoid macular oedema, associated with retinitis pigmentosa, with variable results. The treatment with oral eplerenone might be a good option for the control of this condition.
Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Cystoid macular oedema; Edema macular quístico; Epiretinal membrane; Eplerenona; Eplerenone; Grosor macular; Macular thickness; Membrana epirretiniana; Retinitis pigmentosa; Retinosis pigmetaria

Mesh:

Substances:

Year:  2017        PMID: 28624313     DOI: 10.1016/j.oftal.2017.05.002

Source DB:  PubMed          Journal:  Arch Soc Esp Oftalmol (Engl Ed)        ISSN: 2173-5794


  2 in total

1.  Lipid-based nano-formulation platform for eplerenone oral delivery as a potential treatment of chronic central serous chorioretinopathy: in-vitro optimization and ex-vivo assessment.

Authors:  Eman Abd-Elhakeem; Mohamed El-Nabarawi; Rehab Shamma
Journal:  Drug Deliv       Date:  2021-12       Impact factor: 6.819

2.  Effective Ocular Delivery of Eplerenone Using Nanoengineered Lipid Carriers in Rabbit Model.

Authors:  Eman Abdelhakeem; Mohamed El-Nabarawi; Rehab Shamma
Journal:  Int J Nanomedicine       Date:  2021-07-22
  2 in total

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