Literature DB >> 28623435

The brain behaves as a muscle?

Marinella Coco1.   

Abstract

It is known that lactate accumulates in the skeletal muscle during intense anaerobic exercise but is rapidly cleared from the muscles when they resume aerobic metabolism; however, at least some lactate reaches the blood stream. It has been observed that during maximal exercise, blood lactate increases with transport of the blood to the brain. This could be interpreted as a mechanism to protect against possible "central fatigue" in times of maximal activity during the course of which the lactate would preserve the functionality of the primary cortical motor and sensory areas, even at the expense of the efficiency of the other structures. In this way, the role of lactate, both at the muscular level and in the CNS, appears to shift from being responsible for fatigue to protector from fatigue, which represents a real transition similar to that of how the image of Mr. Hyde changes to that of Dr. Jekyll.

Entities:  

Keywords:  Brain; Fatigue; Lactate; Muscle

Mesh:

Substances:

Year:  2017        PMID: 28623435     DOI: 10.1007/s10072-017-3014-6

Source DB:  PubMed          Journal:  Neurol Sci        ISSN: 1590-1874            Impact factor:   3.307


  30 in total

1.  Effects of heat stress on physiological responses and exercise performance in elite cyclists.

Authors:  A J Tatterson; A G Hahn; D T Martin; M A Febbraio
Journal:  J Sci Med Sport       Date:  2000-06       Impact factor: 4.319

Review 2.  The role of lactate in brain metabolism.

Authors:  Marianne Fillenz
Journal:  Neurochem Int       Date:  2005-11       Impact factor: 3.921

Review 3.  Lactate--a signal coordinating cell and systemic function.

Authors:  Andrew Philp; Adam L Macdonald; Peter W Watt
Journal:  J Exp Biol       Date:  2005-12       Impact factor: 3.312

4.  The rate of heat storage mediates an anticipatory reduction in exercise intensity during cycling at a fixed rating of perceived exertion.

Authors:  Ross Tucker; Trevor Marle; Estelle V Lambert; Timothy D Noakes
Journal:  J Physiol       Date:  2006-02-23       Impact factor: 5.182

5.  Attentional processes during submaximal exercises.

Authors:  Valentina Perciavalle; Giovanna Alagona; Tiziana Maci; Maria Cristina Petralia; Erminio Costanzo; Vincenzo Perciavalle; Marinella Coco
Journal:  Somatosens Mot Res       Date:  2013-06-05       Impact factor: 1.111

6.  Changes in cortical excitability and blood lactate after a fatiguing hand-grip exercise.

Authors:  Marinella Coco; Giovanna Alagona; Valentina Perciavalle; Vincenzo Perciavalle; Paolo Cavallari; Antonio Caronni
Journal:  Somatosens Mot Res       Date:  2013-09-17       Impact factor: 1.111

7.  200th anniversary of lactate research in muscle.

Authors:  L Bruce Gladden
Journal:  Exerc Sport Sci Rev       Date:  2008-07       Impact factor: 6.230

8.  Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Authors:  L Pellerin; P J Magistretti
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

9.  Lactate modulates the activity of primary cortical neurons through a receptor-mediated pathway.

Authors:  Luigi Bozzo; Julien Puyal; Jean-Yves Chatton
Journal:  PLoS One       Date:  2013-08-12       Impact factor: 3.240

10.  Effects of an Exhaustive Exercise on Motor Skill Learning and on the Excitability of Primary Motor Cortex and Supplementary Motor Area.

Authors:  Marinella Coco; Vincenzo Perciavalle; Paolo Cavallari; Valentina Perciavalle
Journal:  Medicine (Baltimore)       Date:  2016-03       Impact factor: 1.889

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  4 in total

1.  Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.

Authors:  Tanja Grubić Kezele; Matea Babić; Dinko Štimac
Journal:  Neurol Sci       Date:  2019-01-18       Impact factor: 3.307

2.  The 2D:4D ratio is associated with performance in the 'TEACCH program' of subjects with autism spectrum disorder.

Authors:  Maria Cristina Petralia; Elisabetta Sagone; Marinella Coco; Raffaele Gueli; Giulia Di Gregorio; Lucio Salvatore Giovanni Coco; Andrea Buscemi; Valentina Perciavalle
Journal:  Exp Ther Med       Date:  2018-10-09       Impact factor: 2.447

Review 3.  Influences of Blood Lactate Levels on Cognitive Domains and Physical Health during a Sports Stress. Brief Review.

Authors:  Marinella Coco; Andrea Buscemi; Tiziana Ramaci; Matej Tusak; Donatella Di Corrado; Vincenzo Perciavalle; Grazia Maugeri; Valentina Perciavalle; Giuseppe Musumeci
Journal:  Int J Environ Res Public Health       Date:  2020-12-04       Impact factor: 3.390

4.  Attentive Processes and Blood Lactate in the Sambo.

Authors:  Marinella Coco; Andrea Buscemi; Matej Tušak; Vincenzo Perciavalle; Alfio Nifosì; Paolo Cavallari; Donatella Di Corrado; Valentina Perciavalle
Journal:  Int J Environ Res Public Health       Date:  2022-01-20       Impact factor: 3.390

  4 in total

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