Literature DB >> 28623241

Suppressing mTORC1 on the lysosome.

Camilla Raiborg1,2, Kay O Schink1,2, Harald Stenmark1,2,3.   

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Year:  2017        PMID： 28623241      PMCID： PMC5502876          DOI： 10.15252/embj.201797469

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


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  9 in total

Review 1.  Regulation of mTORC1 by PI3K signaling.

Authors:  Christian C Dibble; Lewis C Cantley
Journal:  Trends Cell Biol       Date:  2015-07-06       Impact factor: 20.808

2.  mTOR Signaling in Growth, Metabolism, and Disease.

Authors:  Robert A Saxton; David M Sabatini
Journal:  Cell       Date:  2017-04-06       Impact factor: 41.582

3.  Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Authors:  Yasemin Sancak; Liron Bar-Peled; Roberto Zoncu; Andrew L Markhard; Shigeyuki Nada; David M Sabatini
Journal:  Cell       Date:  2010-04-08       Impact factor: 41.582

4.  mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate.

Authors:  Andrea L Marat; Alexander Wallroth; Wen-Ting Lo; Rainer Müller; Giuseppe Danilo Norata; Marco Falasca; Carsten Schultz; Volker Haucke
Journal:  Science       Date:  2017-06-02       Impact factor: 47.728

5.  Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

Authors:  Takahiro Nobukuni; Manel Joaquin; Marta Roccio; Stephen G Dann; So Young Kim; Pawan Gulati; Maya P Byfield; Jonathan M Backer; Francois Natt; Johannes L Bos; Fried J T Zwartkruis; George Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-21       Impact factor: 11.205

6.  Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.

Authors:  Brian M Castellano; Ashley M Thelen; Ofer Moldavski; McKenna Feltes; Reini E N van der Welle; Laurel Mydock-McGrane; Xuntian Jiang; Robert J van Eijkeren; Oliver B Davis; Sharon M Louie; Rushika M Perera; Douglas F Covey; Daniel K Nomura; Daniel S Ory; Roberto Zoncu
Journal:  Science       Date:  2017-03-24       Impact factor: 47.728

7.  Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.

Authors:  T F Franke; D R Kaplan; L C Cantley; A Toker
Journal:  Science       Date:  1997-01-31       Impact factor: 47.728

8.  Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.

Authors:  Dave Bridges; Jing-Tyan Ma; Sujin Park; Ken Inoki; Lois S Weisman; Alan R Saltiel
Journal:  Mol Biol Cell       Date:  2012-06-13       Impact factor: 4.138

9.  Lysosomal positioning coordinates cellular nutrient responses.

Authors:  Viktor I Korolchuk; Shinji Saiki; Maike Lichtenberg; Farah H Siddiqi; Esteban A Roberts; Sara Imarisio; Luca Jahreiss; Sovan Sarkar; Marie Futter; Fiona M Menzies; Cahir J O'Kane; Vojo Deretic; David C Rubinsztein
Journal:  Nat Cell Biol       Date:  2011-03-13       Impact factor: 28.824
  9 in total

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