| Literature DB >> 28622517 |
Benjamin P Garfinkel1, Gökhan S Hotamisligil2.
Abstract
A new mechanism linking ER dysfunction to metabolic inflammation is discovered in a recent study by Shan et al. (2017), which demonstrated ER stress-induced rewiring of adipose tissue macrophage polarization by IRE1α activation, leading to impaired systemic glucose homeostasis.Entities:
Mesh：
Year: 2017 PMID： 28622517 DOI： 10.1016/j.molcel.2017.05.037
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970