Literature DB >> 28622320

A novel graft option after pterygium excision: platelet-rich fibrin for conjunctivoplasty.

H B Cakmak1, G Dereli Can2, M E Can3, N Cagil2.   

Abstract

PurposeTo compare the surgical results, complications, and recurrence rates of primary pterygium excision with conjunctival autografts (CA) vs platelet-rich fibrin (PRF) grafts.Patients and methodsA total of 35 eyes of 35 patients with primary pterygium were included in the study. The patients underwent excision of pterygium followed by closure of the bare sclera by CA (group 1, n=20) vs PRF grafts (group 2, n=15). The PRF was generated from the patients' own whole-blood sample by centrifugation and pressing. The surgery times, intra/postoperative complications, recurrence rates of pterygium, and changes in visual acuity (VA) were evaluated and compared within groups.ResultsThe mean follow-up period was 14.3±6.5 months (6-24 months). The mean preoperative and postoperative VAs were same (20/25) (P=0.204). The mean surgery time was shorter in group 2 (22.1±1.9 min) compared to group 1 (33.8±7.8 min) (P=0.001). The recurrence was observed only in one (6.6%) case of group 2, while none of the cases showed recurrence in group 1. Graft loss was observed in 2 (10%) cases in group 1, and 1 (6.6%) case in group 2. No other intra/postoperative complications such as tear in the graft, excessive bleeding, scleral necrosis, graft necrosis, pannus formation, or symblepharon occurred in both groups.ConclusionsThis preliminary study showed encouraging results of the application of PRF for conjuntivoplasty after pterygium excision. The use of PRF in pterygium surgery is a simple, easily applicable, and a promising method with low rates of recurrence and complications.

Entities:  

Mesh:

Substances:

Year:  2017        PMID: 28622320      PMCID: PMC5684450          DOI: 10.1038/eye.2017.109

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  28 in total

1.  Sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft for pterygium.

Authors:  Hande Taylan Sekeroglu; Elif Erdem; Nese Cetin Dogan; Meltem Yagmur; Reha Ersoz; Ahmet Dogan
Journal:  Int Ophthalmol       Date:  2011-12-07       Impact factor: 2.031

2.  Platelet concentrates: past, present and future.

Authors:  Shobha Prakash; Aditi Thakur
Journal:  J Maxillofac Oral Surg       Date:  2011-02-25

3.  Pterygium and associated ocular surface squamous neoplasia.

Authors:  Lawrence W Hirst; Roy A Axelsen; Ivan Schwab
Journal:  Arch Ophthalmol       Date:  2009-01

Review 4.  Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology.

Authors:  Stephen C Kaufman; Deborah S Jacobs; W Barry Lee; Sophie X Deng; Mark I Rosenblatt; Roni M Shtein
Journal:  Ophthalmology       Date:  2012-10-11       Impact factor: 12.079

5.  Comparing treatment options of pterygium: limbal sliding flap transplantation, primary closing, and amniotic membrane grafting.

Authors:  Sevda Aydin Kurna; Ahmet Altun; Bahtinur Aksu; Riza Kurna; Tomris Sengor
Journal:  Eur J Ophthalmol       Date:  2013-03-12       Impact factor: 2.597

6.  Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision.

Authors:  P Prabhasawat; K Barton; G Burkett; S C Tseng
Journal:  Ophthalmology       Date:  1997-06       Impact factor: 12.079

7.  Evaluation of the recurrence rate for pterygium treated with conjunctival autograft.

Authors:  O Kocamis; M Bilgec
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-09       Impact factor: 3.117

8.  Five-Year Incidence and Predictors for Pterygium in a Rural Community in China: The Yunnan Minority Eye Study.

Authors:  Lan Li; Hua Zhong; Ermiao Tian; Minbin Yu; Yuansheng Yuan; Wenyan Yang; Tao Wei; Xueping Cha; Xun Li; Juanjuan Li; Xiaodan Su; Chen-Wei Pan
Journal:  Cornea       Date:  2015-12       Impact factor: 2.651

9.  Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specifications.

Authors:  Stylianos Serghiou; Chirag J Patel; Yan Yu Tan; Peter Koay; John P A Ioannidis
Journal:  J Clin Epidemiol       Date:  2015-09-28       Impact factor: 6.437

10.  Analysis of recurrence patterns following pterygium surgery with conjunctival autografts.

Authors:  Soo Hyun Kwon; Hong Kyun Kim
Journal:  Medicine (Baltimore)       Date:  2015-01       Impact factor: 1.889

View more
  2 in total

1.  Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer.

Authors:  Dominika Wróbel-Dudzińska; Jorge Alio; Alejandra Rodriguez; Ewa Suchodoła-Ratajewicz; Ewa Kosior-Jarecka; Beata Rymgayłło-Jankowska; Agnieszka Ćwiklińska-Haszcz; Tomasz Żarnowski
Journal:  J Ophthalmol       Date:  2018-06-20       Impact factor: 1.909

2.  Conjunctival Autograft With Fibrin Glue for Pterygium: A Long Term Recurrence Assessment.

Authors:  Pablo Luis Daponte; Andrea Cigna; Ovidio Lescano; Federico Sipowicz; Brenda Peña; Gabriel Abud; Gabriel Di-Virgilio; Adriana Chirinos; Gustavo Federico Bodino
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2019-10-01
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.