Literature DB >> 28621100

Paracetamol infusion-related severe hypotension and cardiac arrest in a child.

Ayhan Yaman1, Baver Demir2, Fatma Burcu Belen3, Bülent Filik2, Necibe Güneş2, Faruk Barlık2, Tanıl Kendirli4.   

Abstract

Paracetamol (also known as Acetaminophen) is an antipyretic, non-opioid analgesic, and non-steroidal anti-inflammatory drug (NSAID), and is one of the most commonly used medications worldwide. In recent years, IV paracetamol has been frequently used in hospitalized patients to reduce fever and pain. Significant adverse reactions associated with intravenous paracetamol are extremely rare. Typically reported adverse events include hypotension, malaise, hypersensitivity reaction, liver enzyme elevation, and thrombocytopenia. We present herein a case of IV paracetamol infusion-related severe hypotension and cardiac arrest.

Entities:  

Keywords:  Paracetamol; cardiac arrest; child; hypotension

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Substances:

Year:  2016        PMID: 28621100     DOI: 10.24953/turkjped.2016.05.016

Source DB:  PubMed          Journal:  Turk J Pediatr        ISSN: 0041-4301            Impact factor:   0.552


  3 in total

1.  Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly.

Authors:  Jennifer van der Horst; Rian W Manville; Katie Hayes; Morten B Thomsen; Geoffrey W Abbott; Thomas A Jepps
Journal:  Arterioscler Thromb Vasc Biol       Date:  2020-03-19       Impact factor: 8.311

2.  Hemodynamic effects of intravenous paracetamol in critically ill children with septic shock on inotropic support.

Authors:  Elhanan Nahum; Avichai Weissbach; Eytan Kaplan; Gili Kadmon
Journal:  J Intensive Care       Date:  2020-01-29

Review 3.  A narrative review of paracetamol-induced hypotension: Keeping the patient safe.

Authors:  Tricia L Young
Journal:  Nurs Open       Date:  2021-06-08
  3 in total

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