BACKGROUND/AIM: Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. MATERIALS AND METHODS: We conducted a cross-sectional questionnaire-based study among a population of 2122 men who underwent andrological investigation for couple infertility. All participants were interviewed and their semen samples were analyzed. Information about medical history and occupational exposure was used to classify participants into exposed and unexposed groups. RESULTS: Exposure to pesticides was associated with a significantly higher risk of asthenozoospermia (adjusted odds ratio [OR] = 1.6; 95% CI, 1.0-2.4) and necrozoospermia (OR = 2.6; 95% CI, 1.4-4.7). Exposure to cement was found to be correlated with a higher risk of oligozoospermia (OR = 1.1; 95% CI, 0.9-1.4). There was no association between semen impairment and exposure to solvents, excess heat, or mechanical vibrations. CONCLUSION: We found an association between self-reported occupational exposure and altered semen parameters. These results support the usefulness of questionnaires for routine assessment and management of occupational exposures in infertile men.
BACKGROUND/AIM: Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. MATERIALS AND METHODS: We conducted a cross-sectional questionnaire-based study among a population of 2122 men who underwent andrological investigation for couple infertility. All participants were interviewed and their semen samples were analyzed. Information about medical history and occupational exposure was used to classify participants into exposed and unexposed groups. RESULTS: Exposure to pesticides was associated with a significantly higher risk of asthenozoospermia (adjusted odds ratio [OR] = 1.6; 95% CI, 1.0-2.4) and necrozoospermia (OR = 2.6; 95% CI, 1.4-4.7). Exposure to cement was found to be correlated with a higher risk of oligozoospermia (OR = 1.1; 95% CI, 0.9-1.4). There was no association between semen impairment and exposure to solvents, excess heat, or mechanical vibrations. CONCLUSION: We found an association between self-reported occupational exposure and altered semen parameters. These results support the usefulness of questionnaires for routine assessment and management of occupational exposures in infertile men.
Entities:
Keywords:
Male infertility; occupational exposure; questionnaire; semen quality
Authors: Ashok Agarwal; Rakesh K Sharma; Sajal Gupta; Florence Boitrelle; Renata Finelli; Neel Parekh; Damayanthi Durairajanayagam; Ramadan Saleh; Mohamed Arafa; Chak Lam Cho; Ala'a Farkouh; Amarnath Rambhatla; Ralf Henkel; Paraskevi Vogiatzi; Nicholas Tadros; Parviz Kavoussi; Edmund Ko; Kristian Leisegang; Hussein Kandil; Ayad Palani; Gianmaria Salvio; Taymour Mostafa; Osvaldo Rajmil; Saleem Ali Banihani; Samantha Schon; Tan V Le; Ponco Birowo; Gökhan Çeker; Juan Alvarez; Juan Manuel Corral Molina; Christopher C K Ho; Aldo E Calogero; Kareim Khalafalla; Mesut Berkan Duran; Shinnosuke Kuroda; Giovanni M Colpi; Armand Zini; Christina Anagnostopoulou; Edoardo Pescatori; Eric Chung; Ettore Caroppo; Fotios Dimitriadis; Germar-Michael Pinggera; Gian Maria Busetto; Giancarlo Balercia; Haitham Elbardisi; Hisanori Taniguchi; Hyun Jun Park; Israel Maldonado Rosas; Jean de la Rosette; Jonathan Ramsay; Kasonde Bowa; Mara Simopoulou; Marcelo Gabriel Rodriguez; Marjan Sabbaghian; Marlon Martinez; Mohamed Ali Sadighi Gilani; Mohamed S Al-Marhoon; Raghavender Kosgi; Rossella Cannarella; Sava Micic; Shinichiro Fukuhara; Sijo Parekattil; Sunil Jindal; Taha Abo-Almagd Abdel-Meguid; Yoshiharu Morimoto; Rupin Shah Journal: World J Mens Health Date: 2021-10-13 Impact factor: 5.400
Authors: Aleksandra Fucic; Karen S Galea; Radu Corneliu Duca; Mounia El Yamani; Nadine Frery; Lode Godderis; Thórhallur Ingi Halldorsson; Ivo Iavicoli; Sophie Ndaw; Edna Ribeiro; Susana Viegas; Hanns Moshammer Journal: Int J Environ Res Public Health Date: 2018-06-11 Impact factor: 3.390