| Literature DB >> 28618263 |
Amanda J Monahan1, Neal Silverman2.
Abstract
Macrophage-mediated bacterial clearance relies on phagocytic uptake of the pathogen, subsequent phagolysosomal maturation, and microbial degradation. In this issue of Cell Host & Microbe, Wong et al. (2017) report that a chloride transporter couples phagocytosis and bacterial clearance in an NF-κB-mediated feedforward loop, which is required for sustained pathogen uptake.Entities:
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Year: 2017 PMID： 28618263 DOI： 10.1016/j.chom.2017.05.013
Source DB: PubMed Journal: Cell Host Microbe ISSN： 1931-3128 Impact factor: 21.023