Literature DB >> 28617504

Biomimetic iterative method for polyketide synthesis.

Kengo Akagawa1, Kazuaki Kudo.   

Abstract

An iterative method for synthesizing polyketides was demonstrated, in which the chain elongation of a carboxylic acid was performed by decarboxylative dehydration condensation with a malonic acid half thioester. After transforming the resulting β-ketothioester into an appropriate form, the carboxylic acid functionality was regenerated for the next elongation step.

Entities:  

Year:  2017        PMID： 28617504     DOI： 10.1039/c7cc04033d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  One-Pot, Highly Stereoselective Synthesis of Dithioacetal-α,α-Diglycosides.

Authors:  Maria F Céspedes Dávila; Jérémy P Schneider; Amélie Godard; Damien Hazelard; Philippe Compain
Journal:  Molecules       Date:  2018-04-15       Impact factor: 4.411

2.  Iterative synthesis of nitrogen-containing polyketide via oxime intermediates.

Authors:  Yuta Takeuchi; Shun Kawasaki; Kengo Akagawa; Kazuaki Kudo
Journal:  RSC Adv       Date:  2022-02-11       Impact factor: 3.361

Review 3.  The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies.

Authors:  Pavan K Mantravadi; Karunakaran A Kalesh; Renwick C J Dobson; André O Hudson; Anutthaman Parthasarathy
Journal:  Antibiotics (Basel)       Date:  2019-01-24

Review 4.  Amino acid-derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development.

Authors:  Anutthaman Parthasarathy; Eli J Borrego; Michael A Savka; Renwick C J Dobson; André O Hudson
Journal:  J Biol Chem       Date:  2021-02-18       Impact factor: 5.157
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.