Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 BAK regulates catalase release from peroxisomes.

Literature DB >> 28616584

BAK regulates catalase release from peroxisomes.

Yukio Fujiki¹, Non Miyata^2,3, Satoru Mukai², Kanji Okumoto², Emily H Cheng⁴.

Abstract

Loss of voltage-dependent anion channel 2 (VDAC2) leads to impaired peroxisome biogenesis in mammalian cells. Knockdown of BAK restores peroxisomal biogenesis in VDAC2-deficient cells, where BAK localization shifts from mitochondria to peroxisomes. Moreover, overexpression of BAK activators in wild-type cells permeabilizes peroxisomes in a BAK-dependent manner. Together, BAK most likely regulates peroxisomal membrane permeability.

Entities: Gene Species

Keywords: Apoptosis; BAK; CHO mutant; VDAC2; catalase; membrane permeabilization; oligomerization; oxidative stress; peroxisome; reactive oxygen species

Year: 2017 PMID： 28616584 PMCID： PMC5462519 DOI： 10.1080/23723556.2017.1306610

Source DB: PubMed Journal: Mol Cell Oncol ISSN： 2372-3556

11 in total

Review 1. The expanding role of mitochondria in apoptosis.

Authors: X Wang
Journal: Genes Dev Date: 2001-11-15 Impact factor: 11.361

Review 2. Mitochondria: releasing power for life and unleashing the machineries of death.

Authors: Donald D Newmeyer; Shelagh Ferguson-Miller
Journal: Cell Date: 2003-02-21 Impact factor: 41.582

3. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.

Authors: Hyungjin Kim; Mubina Rafiuddin-Shah; Ho-Chou Tu; John R Jeffers; Gerard P Zambetti; James J-D Hsieh; Emily H-Y Cheng
Journal: Nat Cell Biol Date: 2006-11-19 Impact factor: 28.824

Review 4. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

Authors: Peter E Czabotar; Guillaume Lessene; Andreas Strasser; Jerry M Adams
Journal: Nat Rev Mol Cell Biol Date: 2014-01 Impact factor: 94.444

Review 5. Mitochondria and cell death: outer membrane permeabilization and beyond.

Authors: Stephen W G Tait; Douglas R Green
Journal: Nat Rev Mol Cell Biol Date: 2010-08-04 Impact factor: 94.444

6. The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes.

Authors: Naomi Matsumoto; Shigehiko Tamura; Yukio Fujiki
Journal: Nat Cell Biol Date: 2003-05 Impact factor: 28.824

7. Relationship Between Catalase and Life Span in Recombinant Inbred Strains of Caenorhabditis elegans.

Authors: Phil Hartman; Patrick Belmont; Sylvia Zuber; Naoaki Ishii; Julie Anderson
Journal: J Nematol Date: 2003-09 Impact factor: 1.402

8. The VDAC2-BAK axis regulates peroxisomal membrane permeability.

Authors: Ken-Ichiro Hosoi; Non Miyata; Satoru Mukai; Satomi Furuki; Kanji Okumoto; Emily H Cheng; Yukio Fujiki
Journal: J Cell Biol Date: 2017-02-07 Impact factor: 10.539

9. An interconnected hierarchical model of cell death regulation by the BCL-2 family.

Authors: Hui-Chen Chen; Masayuki Kanai; Akane Inoue-Yamauchi; Ho-Chou Tu; Yafen Huang; Decheng Ren; Hyungjin Kim; Shugaku Takeda; Denis E Reyna; Po M Chan; Yogesh Tengarai Ganesan; Chung-Ping Liao; Evripidis Gavathiotis; James J Hsieh; Emily H Cheng
Journal: Nat Cell Biol Date: 2015-09-07 Impact factor: 28.824

BAK regulates catalase release from peroxisomes.

Review 1. The expanding role of mitochondria in apoptosis.

Review 2. Mitochondria: releasing power for life and unleashing the machineries of death.

3. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.

Review 4. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

Review 5. Mitochondria and cell death: outer membrane permeabilization and beyond.

6. The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes.

7. Relationship Between Catalase and Life Span in Recombinant Inbred Strains of Caenorhabditis elegans.

8. The VDAC2-BAK axis regulates peroxisomal membrane permeability.

9. An interconnected hierarchical model of cell death regulation by the BCL-2 family.

Review 10. Peroxisome biogenesis in mammalian cells.

Review 1. Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins.

Review 2. Peroxisome: Metabolic Functions and Biogenesis.

Review 3. Subcellular Localization and Dynamics of the Bcl-2 Family of Proteins.

Review 4. The peroxisome: an update on mysteries 2.0.

5. Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner.

6. The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation.