Literature DB >> 2861413

Clonidine accelerates growth in children with impaired growth hormone secretion.

C Pintor, S G Cella, R Corda, V Locatelli, R Puggioni, S Loche, E E Müller.   

Abstract

4 children with isolated growth hormone deficiency (IGHD) and 4 with constitutional growth delay (CGD) were treated with clonidine, 0.1 mg/m2 daily, for 60 days. In 2 children with IGHD and all 4 with CGD, basal growth hormone (GH) and somatomedin-C levels were increased, pituitary GH response to challenges with a synthetic pancreatic GH releasing factor and clonidine was enhanced, and linear growth was stimulated.

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Year:  1985        PMID： 2861413     DOI： 10.1016/s0140-6736(85)92256-1

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  7 in total

Review 1.  Clonidine treatment in children with short stature.

Authors:  S Loche; A Lampis; S G Cella; V Locatelli; E E Müller; C Pintor
Journal:  J Endocrinol Invest       Date:  1988-11       Impact factor: 4.256

Review 2.  Intranasal drug delivery. Potential advantages and limitations from a clinical pharmacokinetic perspective.

Authors:  A E Pontiroli; A Calderara; G Pozza
Journal:  Clin Pharmacokinet       Date:  1989-11       Impact factor: 6.447

Review 3.  Growth hormone therapy in Canada: end of one era and beginning of another.

Authors:  H J Dean; H G Friesen
Journal:  CMAJ       Date:  1986-08-15       Impact factor: 8.262

Review 4.  Neuroendocrine regulation of human growth hormone secretion. Diagnostic and clinical applications.

Authors:  G Delitala; P Tomasi; R Virdis
Journal:  J Endocrinol Invest       Date:  1988-06       Impact factor: 4.256

5.  One year treatment with clonidine in children with constitutional growth delay.

Authors:  B Moreno Esteban; S Monereo Mejías; P Rodríguez Poyo-Guerrero; F J Moreno Esteban; J A Tresguerres
Journal:  J Endocrinol Invest       Date:  1991-02       Impact factor: 4.256

6.  Growth rate and growth hormone response to growth hormone-releasing hormone challenge in slowly growing children during chronic administration of clonidine.

Authors:  F Orio; N Padovano; L Cinquanta; A Colao; B Merola; S Longobardi; E Rossi; V Esposito; F Orio; G Lombardi
Journal:  J Endocrinol Invest       Date:  1995-01       Impact factor: 4.256

7.  Acute administration of pyridostigmine and clonidine has an additive stimulatory effect on GH release in normal children.

Authors:  E Ghigo; S Goffi; E Mazza; E Imperiale; E Arvat; J Bellone; M Procopio; E E Müller; F Camanni
Journal:  J Endocrinol Invest       Date:  1989-02       Impact factor: 4.256
  7 in total

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