Literature DB >> 28614011

Structural Basis for CD4+ T Cell Epitope Dominance in Arbo-Flavivirus Envelope Proteins: A Meta-Analysis.

Samuel J Landry1, Daniel L Moss1, Da Cui1, Ryan P Ferrie1, Mitchell L Fullerton1, Evan A Wells1, Lu Yang1, Nini Zhou1, Thomas Dougherty1, Ramgopal R Mettu2.   

Abstract

A meta-analysis of CD4+ T cell epitope maps reveals clusters and gaps in envelope-protein (E protein) immunogenicity that can be explained by the likelihood of epitope processing, as determined by E protein three-dimensional structures. Differential processing may be at least partially responsible for variations in disease severity among arbo-flaviruses and points to structural features that modulate protection from disease.

Entities:  

Keywords:  antigen processing; class II MHC protein; helper T cell

Mesh：

Substances：

Year:  2017        PMID： 28614011      PMCID： PMC5610399          DOI： 10.1089/vim.2017.0008

Source DB:  PubMed          Journal:  Viral Immunol        ISSN： 0882-8245            Impact factor:   2.257


  58 in total

1.  Control of antigen presentation by a single protease cleavage site.

Authors:  A N Antoniou; S L Blackwood; D Mazzeo; C Watts
Journal:  Immunity       Date:  2000-04       Impact factor: 31.745

2.  Cutting edge: introduction of an endopeptidase cleavage motif into a determinant flanking region of hen egg lysozyme results in enhanced T cell determinant display.

Authors:  S C Schneider; J Ohmen; L Fosdick; B Gladstone; J Guo; A Ametani; E E Sercarz; H Deng
Journal:  J Immunol       Date:  2000-07-01       Impact factor: 5.422

Review 3.  Flavivirus membrane fusion.

Authors:  Karin Stiasny; Franz X Heinz
Journal:  J Gen Virol       Date:  2006-10       Impact factor: 3.891

4.  Evidence of Sexual Transmission of Zika Virus.

Authors:  Eric D'Ortenzio; Sophie Matheron; Yazdan Yazdanpanah; Xavier de Lamballerie; Bruno Hubert; Géraldine Piorkowski; Marianne Maquart; Diane Descamps; Florence Damond; Isabelle Leparc-Goffart
Journal:  N Engl J Med       Date:  2016-04-13       Impact factor: 91.245

5.  CD4+ T-cell epitope prediction using antigen processing constraints.

Authors:  Ramgopal R Mettu; Tysheena Charles; Samuel J Landry
Journal:  J Immunol Methods       Date:  2016-02-15       Impact factor: 2.303

6.  T-helper cell epitopes on the E-glycoprotein of dengue 2 Jamaica virus.

Authors:  J T Roehrig; P A Risi; J R Brubaker; A R Hunt; B J Beaty; D W Trent; J H Mathews
Journal:  Virology       Date:  1994-01       Impact factor: 3.616

Review 7.  Flaviviruses, an expanding threat in public health: focus on dengue, West Nile, and Japanese encephalitis virus.

Authors:  Carlo Amorin Daep; Jorge L Muñoz-Jordán; Eliseo Alberto Eugenin
Journal:  J Neurovirol       Date:  2014-10-07       Impact factor: 2.643

8.  Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells.

Authors:  E Fiebiger; P Meraner; E Weber; I F Fang; G Stingl; H Ploegh; D Maurer
Journal:  J Exp Med       Date:  2001-04-16       Impact factor: 14.307

9.  Human T cell responses to Japanese encephalitis virus in health and disease.

Authors:  Lance Turtle; Tanushka Bali; Gemma Buxton; Savita Chib; Sajesh Chan; Mohammed Soni; Mohammed Hussain; Heather Isenman; Prachi Fadnis; Manjunatha M Venkataswamy; Vishali Satishkumar; Penny Lewthwaite; Ayako Kurioka; Srinivasa Krishna; M Veera Shankar; Riyaz Ahmed; Ashia Begum; Vasanthapuram Ravi; Anita Desai; Sutee Yoksan; Stefan Fernandez; Christian B Willberg; Henrik N Kloverpris; Christopher Conlon; Paul Klenerman; Vijaya Satchidanandam; Tom Solomon
Journal:  J Exp Med       Date:  2016-05-30       Impact factor: 14.307

10.  Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help.

Authors:  Norifumi Iijima; Akiko Iwasaki
Journal:  Nature       Date:  2016-05-18       Impact factor: 49.962
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  2 in total

1.  CD4 T Cell Determinants in West Nile Virus Disease and Asymptomatic Infection.

Authors:  Maximilian Koblischke; Felicia S Spitzer; David M Florian; Stephan W Aberle; Stefan Malafa; Ingrid Fae; Irene Cassaniti; Christof Jungbauer; Bernhard Knapp; Hermann Laferl; Gottfried Fischer; Fausto Baldanti; Karin Stiasny; Franz X Heinz; Judith H Aberle
Journal:  Front Immunol       Date:  2020-01-23       Impact factor: 7.561

2.  Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection.

Authors:  Maximilian Koblischke; Karin Stiasny; Stephan W Aberle; Stefan Malafa; Georgios Tsouchnikas; Julia Schwaiger; Michael Kundi; Franz X Heinz; Judith H Aberle
Journal:  Front Immunol       Date:  2018-05-30       Impact factor: 7.561
  2 in total

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