Literature DB >> 28613312

Highly efficient complexation of sanguinarine alkaloid by carboxylatopillar[6]arene: pKa shift, increased solubility and enhanced antibacterial activity.

Guchuan Ping1, Yiliang Wang, Lingyun Shen, Yuting Wang, Xiaoshi Hu, Junyi Chen, Bingwen Hu, Lei Cui, Qingbin Meng, Chunju Li.   

Abstract

Encapsulation of a physiologically active substance, sanguinarine (SA), by a water soluble carboxylatopillar[6]arene (CP6A), is described. The efficient complexation by CP6A, giving a Ka value of (2.4 ± 0.3) × 105 M-1 in pH 7.4, served to increase the water solubility by 4.3-fold, cause a 2.02 shift in pKa, and enhance the antibacterial activity of SA.

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Year:  2017        PMID： 28613312     DOI： 10.1039/c7cc02799k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Noninvasive and Individual-Centered Monitoring of Uric Acid for Precaution of Hyperuricemia via Optical Supramolecular Sensing.

Authors:  Yaping Zhang; Huijuan Yu; Shiwei Chai; Xin Chai; Luyao Wang; Wen-Chao Geng; Juan-Juan Li; Yu-Xin Yue; Dong-Sheng Guo; Yuefei Wang
Journal:  Adv Sci (Weinh)       Date:  2022-04-28       Impact factor: 17.521

2.  Supramolecular interaction of sanguinarine dye with sulfobutylether-β-cyclodextrin: modulation of the photophysical properties and antibacterial activity.

Authors:  Vidya Kadam; Aarti S Kakatkar; Nilotpal Barooah; Suchandra Chatterjee; Achikanath C Bhasikuttan; Jyotirmayee Mohanty
Journal:  RSC Adv       Date:  2020-07-03       Impact factor: 4.036

3.  Monosulfonicpillar[5]arene: Synthesis, Characterization, and Complexation with Tetraphenylethene for Aggregation-Induced Emission.

Authors:  Xiao-Yu Jin; Nan Song; Xu Wang; Chun-Yu Wang; Yan Wang; Ying-Wei Yang
Journal:  Sci Rep       Date:  2018-03-05       Impact factor: 4.379

4.  Ultrasensitive and specific fluorescence detection of a cancer biomarker via nanomolar binding to a guanidinium-modified calixarene.

Authors:  Zhe Zheng; Wen-Chao Geng; Jie Gao; Yu-Ying Wang; Hongwei Sun; Dong-Sheng Guo
Journal:  Chem Sci       Date:  2018-01-09       Impact factor: 9.825

Review 5.  Supramolecular nanotheranostics based on pillarenes.

Authors:  Nan Song; Xin-Yue Lou; Lianjun Ma; Hui Gao; Ying-Wei Yang
Journal:  Theranostics       Date:  2019-05-18       Impact factor: 11.556

6.  pH-Induced Transition Between Single-Chain Macrocyclic Amphiphile and [c2]Daisy Chain-Based Bola-Type Amphiphile and the Related Self-Assembly Behavior in Water.

Authors:  Pi Wang; Ruihuan Wang; Danyu Xia
Journal:  Front Chem       Date:  2020-01-24       Impact factor: 5.221

Review 7.  Technologies for Solubility, Dissolution and Permeation Enhancement of Natural Compounds.

Authors:  Meshal Alshamrani; Muhammad Khalid Khan; Barkat Ali Khan; Ahmad Salawi; Yosif Almoshari
Journal:  Pharmaceuticals (Basel)       Date:  2022-05-25

8.  Enhancing Mechanical Performance of a Polymer Material by Incorporating Pillar[5]arene-Based Host-Guest Interactions.

Authors:  Chengdi Huang; Hanwei Zhang; Ziqing Hu; Youping Zhang; Xiaofan Ji
Journal:  Gels       Date:  2022-07-28

9.  Synthesis of diamido-bridged bis-pillar[5]arenes and tris-pillar[5]arenes for construction of unique [1]rotaxanes and bis-[1]rotaxanes.

Authors:  Ying Han; Li-Ming Xu; Cui-Yun Nie; Shuo Jiang; Jing Sun; Chao-Guo Yan
Journal:  Beilstein J Org Chem       Date:  2018-07-04       Impact factor: 2.883

10.  Synthesis of a water-soluble 2,2'-biphen[4]arene and its efficient complexation and sensitive fluorescence enhancement towards palmatine and berberine.

Authors:  Xiayang Huang; Xinghua Zhang; Tianxin Qian; Junwei Ma; Lei Cui; Chunju Li
Journal:  Beilstein J Org Chem       Date:  2018-08-27       Impact factor: 2.883
  10 in total

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