Literature DB >> 28612149

35-Year Experience with Surgical Treatment of Hidradenitis Suppurativa.

Richard E Burney1.   

Abstract

BACKGROUND: Hidradenitis suppurativa is a painful and disfiguring chronic inflammatory condition affecting both men and women. Medical treatments, such as antibiotics and immunosuppressive agents, are often ineffective. Over time, patients can suffer from recurrent abscesses, chronic purulent drainage, scarring, and contractures that can only be corrected by surgical excision. There is no agreement, however, on the best way for the surgeon to manage this condition. The purpose of this review is to describe the results of surgical treatment of this condition in a large cohort of patients managed by local excision of hidradenitis, healing by secondary intention and reoperation as needed. STUDY
DESIGN: A retrospective review was conducted of all patients operated on by the author for hidradenitis over a 35-year period. Specific data abstracted included patient age, weight, admission, length of stay, wound size, type of wound care, number of post-op visits, time to heal, and recurrence. Most wounds healed by secondary intention and were managed using simple tap water-moistened plain gauze dressings changed three times a day.
RESULTS: From 1979 through 2014, 122 patients (56 men and 66 women), median age 38, underwent 245 operations for hidradenitis suppurativa. Patients underwent from 1 to 10 procedures; 61 patients (50%) underwent two or more procedures; and 26 (21%) underwent three or more. Wound sizes at operation ranged from quite small to over 1500 cm2. Men were older (42 vs 34 years, p < 0.001) and had larger median wound size (98 vs 55 cm2, p < 0.001). A total of 197 wounds healed by secondary intention: 83 of these (median size 159 cm2) were left completely open at the time of surgery; 117 (median size 100 cm2) were partially closed. A total of 30 wounds (median size 38 cm2) were closed primarily; 15 (median size 196 cm2) were closed by skin graft. Patients undergoing 139 procedures were admitted to the hospital for the initial wound care. Their median combined total wound size was 160 cm2; length of stay was 5.5 days; and median time to heal was 60 days. In total, 106 procedures were ambulatory; median wound size was 30 cm2; and median time to heal was 40 days. Recurrent or new disease was common, with some patients requiring multiple procedures over many years to maintain control of symptoms. Although wound healing can take up to several months, patients quickly learned how to care for themselves and were usually pain-free after the first two or three weeks.
CONCLUSIONS: Surgical treatment of hidradenitis suppurativa by wide local excision with healing by secondary intention using tap water-moistened plain gauze dressings changed 2-3 times per day is a simple, practical approach that has good results. Recurrence of disease is common and should not be thought of as a failure of surgical treatment, but rather as a feature of the disease that must be anticipated and managed.

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Year:  2017        PMID: 28612149     DOI: 10.1007/s00268-017-4091-7

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  8 in total

1.  Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig.

Authors:  G D WINTER
Journal:  Nature       Date:  1962-01-20       Impact factor: 49.962

Review 2.  Hidradenitis suppurativa: a comprehensive review.

Authors:  Ali Alikhan; Peter J Lynch; Daniel B Eisen
Journal:  J Am Acad Dermatol       Date:  2009-04       Impact factor: 11.527

3.  Hidradenitis suppurativa of the groin, treated by excision and spontaneous healing.

Authors:  S Ariyan; T J Krizek
Journal:  Plast Reconstr Surg       Date:  1976-07       Impact factor: 4.730

4.  Long-term results of wide surgical excision in 106 patients with hidradenitis suppurativa.

Authors:  R Rompel; J Petres
Journal:  Dermatol Surg       Date:  2000-07       Impact factor: 3.398

5.  Surgical Management of Hidradenitis Suppurativa: Outcomes of 590 Consecutive Patients.

Authors:  John J Kohorst; Christian L Baum; Clark C Otley; Randall K Roenigk; Louis A Schenck; John H Pemberton; Eric J Dozois; Nho V Tran; Alex Senchenkov; Mark D P Davis
Journal:  Dermatol Surg       Date:  2016-09       Impact factor: 3.398

6.  Hidradenitis suppurativa: patient satisfaction with wound healing by secondary intention.

Authors:  B Silverberg; C E Smoot; S J Landa; R W Parsons
Journal:  Plast Reconstr Surg       Date:  1987-04       Impact factor: 4.730

7.  A comparison of skin grafting and healing by granulation, following axillary excision for hidradenitis suppurativa.

Authors:  W P Morgan; K G Harding; L E Hughes
Journal:  Ann R Coll Surg Engl       Date:  1983-07       Impact factor: 1.891

8.  Granulation tissue as a contractile organ. A study of structure and function.

Authors:  G Gabbiani; B J Hirschel; G B Ryan; P R Statkov; G Majno
Journal:  J Exp Med       Date:  1972-04-01       Impact factor: 14.307

  8 in total
  5 in total

1.  Impact of 970 nm photobiomodulation therapy on wound healing in cellular models of hidradenitis suppurativa.

Authors:  Luisa Zupin; Giulia Ferri; Paola Maura Tricarico; Rossella Gratton; Cécile Nait-Meddour; Giulia Ottaviani; Sergio Crovella
Journal:  Lasers Med Sci       Date:  2020-07-09       Impact factor: 3.161

2.  Factors influencing the local cure rate of hidradenitis suppurativa following wide local excision.

Authors:  Ledibabari M Ngaage; Yinglun Wu; Shealinna Ge; Selim Gebran; Fan Liang; Erin M Rada; Arthur J Nam; Ronald P Silverman; Yvonne M Rasko
Journal:  Int Wound J       Date:  2019-11-03       Impact factor: 3.315

Review 3.  Surgical Management of Hidradenitis Suppurativa: A Narrative Review.

Authors:  Surbhi Chawla; Connor Toale; Marie Morris; A M Tobin; Dara Kavanagh
Journal:  J Clin Aesthet Dermatol       Date:  2022-01

Review 4.  Surgical Treatment in Hidradenitis Suppurativa.

Authors:  Ratnakar Shukla; Priyanka Karagaiah; Anant Patil; Katherine Farnbach; Alex G Ortega-Loayza; Thrasivoulos Tzellos; Jacek C Szepietowski; Mario Giulini; Hadrian Schepler; Stephan Grabbe; Mohamad Goldust
Journal:  J Clin Med       Date:  2022-04-21       Impact factor: 4.964

5.  Histologic progression of acne inversa/hidradenitis suppurativa: Implications for future investigations and therapeutic intervention.

Authors:  Robert W Dunstan; Katherine M Salte; Viktor Todorović; Margaret Lowe; Joseph B Wetter; Paul W Harms; Richard E Burney; Victoria E Scott; Kathleen M Smith; Michael D Rosenblum; Johann E Gudjonsson; Prisca Honore
Journal:  Exp Dermatol       Date:  2021-01-20       Impact factor: 3.960

  5 in total

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