Literature DB >> 28610940

Establishment of a research pharmacy to support Ebola clinical research in Liberia.

Jerome F Pierson, Matthew Carl Kirchoff, Rev Tijli Tyee, Michael J Montello, Julie K Rhie.   

Abstract

OBJECTIVE: This article describes the establishment of a research pharmacy to support the Partnership for Research on Ebola Vaccines in Liberia (PREVAIL) vaccine study for Ebola virus disease.
SETTING: This article describes the establishment of the pharmacy element to support the overall research program during an Ebola outbreak in Monrovia, Liberia, in 2014 and 2015. PRACTICE INNOVATION: The need for the rapid establishment of infrastructure to support the Liberia-United States joint clinical research partnership in response to the emerging Ebola virus disease provided the opportunity for collaboration among Liberian and U.S. pharmacists. PRACTICE DESCRIPTION: Resource austere and research naïve. EVALUATION: Research pharmacy prepared and randomized 1500 vaccinations in support of PREVAIL.
RESULTS: Experiences of the Liberian and U.S. pharmacists involved in the program are described.
CONCLUSION: The partnership was successful in the conduct of the study. More importantly, the capacity for Liberian pharmacists to support clinical research was established. In addition, the U.S. team learned several important lessons that will help prepare them for responding to research needs in future infectious disease outbreaks. Published by Elsevier Inc.

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Year:  2017        PMID: 28610940      PMCID: PMC5513750          DOI: 10.1016/j.japh.2017.04.002

Source DB:  PubMed          Journal:  J Am Pharm Assoc (2003)        ISSN: 1086-5802


  5 in total

1.  Instruction on compounded sterile preparations at U.S. schools of pharmacy.

Authors:  Mac Hellums; Susan P Alverson; Mary R Monk-Tutor
Journal:  Am J Health Syst Pharm       Date:  2007-11-01       Impact factor: 2.637

Review 2.  Effectively introducing a new meningococcal A conjugate vaccine in Africa: the Burkina Faso experience.

Authors:  Mamoudou H Djingarey; Rodrigue Barry; Mete Bonkoungou; Sylvestre Tiendrebeogo; Rene Sebgo; Denis Kandolo; Clement Lingani; Marie-Pierre Preziosi; Patrick L F Zuber; William Perea; Stéphane Hugonnet; Nora Dellepiane de Rey Tolve; Carole Tevi-Benissan; Thomas A Clark; Leonard W Mayer; Ryan Novak; Nancy E Messonier; Monique Berlier; Desire Toboe; Deo Nshimirimana; Richard Mihigo; Teresa Aguado; Fabien Diomandé; Paul A Kristiansen; Dominique A Caugant; F Marc Laforce
Journal:  Vaccine       Date:  2012-05-30       Impact factor: 3.641

3.  Implementation of an Ebola virus disease vaccine clinical trial during the Ebola epidemic in Liberia: Design, procedures, and challenges.

Authors:  Stephen B Kennedy; James D Neaton; H Clifford Lane; Mark W S Kieh; Moses B F Massaquoi; Nancy A Touchette; Martha C Nason; Dean A Follmann; Fatorma K Boley; Melvin P Johnson; Gregg Larson; Francis N Kateh; Tolbert G Nyenswah
Journal:  Clin Trials       Date:  2016-01-14       Impact factor: 2.486

4.  Conducting clinical trials in outbreak settings: Points to consider.

Authors:  H Clifford Lane; Hilary D Marston; Anthony S Fauci
Journal:  Clin Trials       Date:  2016-01-14       Impact factor: 2.486

5.  Epidemiological and Surveillance Response to Ebola Virus Disease Outbreak in Lofa County, Liberia (March-September, 2014); Lessons Learned.

Authors:  Koffi Isidore Kouadio; Peter Clement; Josephus Bolongei; Alpha Tamba; Alex Ntale Gasasira; Abdihamid Warsame; Joseph Chukwudi Okeibunor; Martin Okechukwu Ota; Boima Tamba; Nicksy Gumede; Keith Shaba; Alain Poy; Mbaye Salla; Richard Mihigo; Deo Nshimirimana
Journal:  PLoS Curr       Date:  2015-05-06
  5 in total

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