Literature DB >> 2860904

Effect of somatostatin on the proliferation of mouse spleen lymphocytes in vitro.

M Pawlikowski, H Stepien, J Kunert-Radek, A V Schally.   

Abstract

The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated in vitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10(-7) M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.

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Year:  1985        PMID： 2860904     DOI： 10.1016/0006-291x(85)91401-9

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

1.  Distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches.

Authors:  E Fehér; M Fodor; G Burnstock
Journal:  Gut       Date:  1992-09       Impact factor: 23.059

2.  Measles virus modulates human T-cell somatostatin receptors and their coupling to adenylyl cyclase.

Authors:  S Krantic; A Enjalbert; C Rabourdin-Combe
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

3.  Evidence that somatostatin is localized and synthesized in lymphoid organs.

Authors:  M C Aguila; W L Dees; W E Haensly; S M McCann
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

4.  Somatostatin analogue scintigraphy in granulomatous diseases.

Authors:  P M Vanhagen; E P Krenning; J C Reubi; D J Kwekkeboom; W H Bakker; A H Mulder; I Laissue; H C Hoogstede; S W Lamberts
Journal:  Eur J Nucl Med       Date:  1994-06

5.  Effect of high doses of somatostatin on adenylate cyclase activity in peripheral mononuclear leukocytes from normal subjects and from acute leukemia patients.

Authors:  M Peracchi; F Bamonti-Catena; B Bareggi
Journal:  Experientia       Date:  1988-07-15

6.  The paradoxical effects of somatostatin on the bioactivity and production of cytotoxins derived from human peripheral blood mononuclear cells.

Authors:  S Yousefi; N Vaziri; G Carandang; W Le; R Yamamoto; G Granger; J Ocariz; T Cesario
Journal:  Br J Cancer       Date:  1991-08       Impact factor: 7.640

7.  Somatostatin in inflammatory bowel disease.

Authors:  J D van Bergeijk; J H Wilson
Journal:  Mediators Inflamm       Date:  1997       Impact factor: 4.711

Review 8.  Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease.

Authors:  Magdy El-Salhy; Tefera Solomon; Trygve Hausken; Odd Helge Gilja; Jan Gunnar Hatlebakk
Journal:  World J Gastroenterol       Date:  2017-07-28       Impact factor: 5.742

9.  REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis.

Authors:  Rodrick Montjean; Sonia Escaich; Raffaello Paolini; Claude Carelli; Sébastien Pirson; Thibaut Neutelings; Yves Henrotin; Christelle Vêtu
Journal:  PLoS One       Date:  2020-04-14       Impact factor: 3.240
  9 in total

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