| Literature DB >> 28608448 |
Xiaoxu Qi1, Pinhong Chen1, Guosheng Liu1.
Abstract
A catalytic intermolecular allylic C-H trifluoromethoxylation reaction of alkenes has been developed based on the use of a palladium catalyst, CsOCF3 as the trifluoromethoxide source, and benzoquinone as the oxidant. This reaction provides an efficient route for directly accessing allylic trifluoromethoxy derivatives with excellent regioselectivities from terminal alkenes via an allylic C-H bond activation process.Entities:
Keywords: C−H activation; alkenes; fluorine; palladium catalysis; trifluoromethoxylation
Year: 2017 PMID： 28608448 DOI： 10.1002/anie.201703841
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336