Literature DB >> 28607897

A Comparative Study of Pharyngeal Repair in Two Layers Versus Three Layers, Following Total Laryngectomy in Carcinoma of Larynx.

Asok K Saha1,2, Saikat Samaddar1, Avijit Choudhury1, Abir Chaudhury1, Nirmalya Roy1.   

Abstract

Larynx is the second most common site for cancer in the upper aerodigestive tract. One of the dreaded complications following total laryngectomy has been pharyngo cutaneous fistula (PCF). PCF merits special attention due to its significant negative impact on the recovery process. Total laryngectomy profoundly alters speech. Effective voice restoration is essential for the rehabilitation of these patients. Inadequate consensus exists as to the best technique of pharyngeal repair to decrease incidence of PCF and ensure good quality voice following total laryngectomy. 21 patients were included in the study for total laryngectomy with trachea oesophageal voice prosthesis placement. Patients were randomised into 2 groups. Group A had their pharynx repaired in two layers and Group B had it done in three layers. Post operatively the patients were followed up for a period of 12 months to look for incidence of PCF. Subjective and objective evaluation of voice was done. 9.52% of patients developed PCF. All of the cases of PCF were in the group repaired in three layers. In cases with repair by two layers the mean Voice Handicap Index 10 (VHI 10) score was 19.27 and those with three layers pharyngeal repair was 23.20. Average maximum phonation time amongst the study population was 13.09. In three layers and two layers pharyngeal repair the average maximum phonation time was 12.56 and 13.58 respectively. Surgical repair of pharynx in two layers excluding the third layer of pharyngeal musculature reduces the chance of PCF. Two layers pharyngeal repair supplemented by cricopharyngeal myotomy led to significantly better voice outcome.

Entities:  

Keywords:  Laryngeal neoplasms; Laryngectomy; Neoplasm staging; Pharyngectomy; Speech; Suture techniques

Year:  2017        PMID: 28607897      PMCID: PMC5446349          DOI: 10.1007/s12070-017-1108-3

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  16 in total

1.  Pectoralis myofascial flap during salvage laryngectomy prevents pharyngocutaneous fistula.

Authors:  Urjeet A Patel; Sanjay P Keni
Journal:  Otolaryngol Head Neck Surg       Date:  2009-08       Impact factor: 3.497

2.  Pharyngo-cutaneous fistulae after laryngectomy. Influence of previous radiotherapy and prophylactic metronidazole.

Authors:  L V Johansen; J Overgaard; O Elbrønd
Journal:  Cancer       Date:  1988-02-15       Impact factor: 6.860

3.  An endoscopic technique for restoration of voice after laryngectomy.

Authors:  M I Singer; E D Blom
Journal:  Ann Otol Rhinol Laryngol       Date:  1980 Nov-Dec       Impact factor: 1.547

Review 4.  Surgical voice restoration after total laryngectomy: an overview.

Authors:  B Elmiyeh; R C Dwivedi; N Jallali; E J Chisholm; R Kazi; P M Clarke; P H Rhys-Evans
Journal:  Indian J Cancer       Date:  2010 Jul-Sep       Impact factor: 1.224

5.  Incidence and predisposing factors of pharyngocutaneous fistula formation after total laryngectomy. Is there a relationship with tumor recurrence?

Authors:  Konstantinos D Markou; Konstantinos C Vlachtsis; Angelos C Nikolaou; Dimitrios G Petridis; Athanasios I Kouloulas; Ioannis C Daniilidis
Journal:  Eur Arch Otorhinolaryngol       Date:  2003-07-10       Impact factor: 2.503

6.  Development and validation of the voice handicap index-10.

Authors:  Clark A Rosen; Annie S Lee; Jamie Osborne; Thomas Zullo; Thomas Murry
Journal:  Laryngoscope       Date:  2004-09       Impact factor: 3.325

7.  Continuous versus interrupted suture techniques of pancreaticojejunostomy after pancreaticoduodenectomy.

Authors:  Yonghua Chen; Nengwen Ke; Chunlu Tan; Hao Zhang; Xing Wang; Gang Mai; Xubao Liu
Journal:  J Surg Res       Date:  2014-08-05       Impact factor: 2.192

8.  The assessment of pharyngocutaneous fistula rate in patients treated primarily with definitive radiotherapy followed by salvage surgery of the larynx and hypopharynx.

Authors:  Richard Dirven; Brian D Swinson; Kan Gao; Jonathan R Clark
Journal:  Laryngoscope       Date:  2009-09       Impact factor: 3.325

9.  Primary closure of pharyngeal remnant after total laryngectomy and partial pharyngectomy: how much residual mucosa is sufficient?

Authors:  Y Hui; W I Wei; P W Yuen; L K Lam; W K Ho
Journal:  Laryngoscope       Date:  1996-04       Impact factor: 3.325

10.  Modified Continuous Mucosal Connell Suture for the Pharyngeal Closure After Total Laryngectomy: Zipper Suture.

Authors:  Mehmet Haksever; Davut Akduman; Sundus Aslan; Fevzi Solmaz; Suay Ozmen
Journal:  Clin Exp Otorhinolaryngol       Date:  2015-08-13       Impact factor: 3.372

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