Literature DB >> 28607087

Remodeling vancomycin yields a victory in the battle against bacteria.

Steven L Castle1.   

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Year:  2017        PMID： 28607087      PMCID： PMC5495287          DOI： 10.1073/pnas.1707728114

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  10 in total

1.  Partitioning the loss in vancomycin binding affinity for D-Ala-D-Lac into lost H-bond and repulsive lone pair contributions.

Authors:  Casey C McComas; Brendan M Crowley; Dale L Boger
Journal:  J Am Chem Soc       Date:  2003-08-06       Impact factor: 15.419

Review 2.  Glycopeptide and lipoglycopeptide antibiotics.

Authors:  Dan Kahne; Catherine Leimkuhler; Wei Lu; Christopher Walsh
Journal:  Chem Rev       Date:  2005-02       Impact factor: 60.622

3.  The drug-resistant bacteria that pose the greatest health threats.

Authors:  Cassandra Willyard
Journal:  Nature       Date:  2017-02-28       Impact factor: 49.962

4.  Antibiotic effectiveness: balancing conservation against innovation.

Authors:  Ramanan Laxminarayan
Journal:  Science       Date:  2014-09-12       Impact factor: 47.728

Review 5.  Regulatory Incentives for Antibiotic Drug Development: A Review of Recent Proposals.

Authors:  Michael S Sinha; Aaron S Kesselheim
Journal:  Bioorg Med Chem       Date:  2016-08-22       Impact factor: 3.641

6.  Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics.

Authors:  Akinori Okano; Atsushi Nakayama; Kejia Wu; Erick A Lindsey; Alex W Schammel; Yiqing Feng; Karen C Collins; Dale L Boger
Journal:  J Am Chem Soc       Date:  2015-03-09       Impact factor: 15.419

7.  Total synthesis and evaluation of [Psi[CH2NH]Tpg4]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

Authors:  Brendan M Crowley; Dale L Boger
Journal:  J Am Chem Soc       Date:  2006-03-08       Impact factor: 15.419

Review 8.  Vancomycin resistance: decoding the molecular logic.

Authors:  C T Walsh
Journal:  Science       Date:  1993-07-16       Impact factor: 47.728

9.  Peripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics.

Authors:  Akinori Okano; Nicholas A Isley; Dale L Boger
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-30       Impact factor: 11.205

10.  Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate.

Authors:  Lan Chen; Deborah Walker; Binyuan Sun; Yanan Hu; Suzanne Walker; Daniel Kahne
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-24       Impact factor: 11.205
  10 in total

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