Hui Xu1, Yu Ding2, Yue Ma3, Xueling Xin4, Dongfeng Zhang5. 1. Department of Epidemiology and Health Statistics, School of Public Health of Qingdao University, Qingdao, Shandong Province, People's Republic of China. Electronic address: xuhui715@126.com. 2. Department of Reproduction, Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People's Republic of China. Electronic address: dingyu0304@126.com. 3. Department of Epidemiology and Health Statistics, School of Public Health of Qingdao University, Qingdao, Shandong Province, People's Republic of China. Electronic address: murphy.ma@163.com. 4. Department of Epidemiology and Health Statistics, School of Public Health of Qingdao University, Qingdao, Shandong Province, People's Republic of China. Electronic address: axin9026@163.com. 5. Department of Epidemiology and Health Statistics, School of Public Health of Qingdao University, Qingdao, Shandong Province, People's Republic of China. Electronic address: zhangdf1961@126.com.
Abstract
OBJECTIVE: The association of cesarean section (CS) with the risk of postpartum depression (PPD) remains controversial. Therefore, we conducted a meta-analysis to explore the association between CS and the risk of PPD. METHODS: A systematic literature search was performed in PubMed, Web of Science and Embase databases for relevant articles up to November 2016. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated with fixed-effects model or random-effects model. RESULTS: A total of 28 studies from 27 articles involving 532,630 participants were included in this meta-analysis. The pooled OR of the association between CS and PPD risk was 1.26 (95% CI: 1.16-1.36). In subgroup analyses stratified by study design [cohort studies: (1.25, 95% CI: 1.10-1.41); case-control studies: (1.25, 95% CI: 1.00-1.56); cross-sectional studies: (1.44, 95% CI: 1.14-1.82)] and adjustment status of complications during pregnancy [adjusted for: (1.29, 95% CI: 1.12-1.48); not-adjusted for: (1.24, 95% CI: 1.13-1.36)], the above-mentioned associations remained consistent. The pooled ORs of PPD were 1.15 (95% CI: 0.92-1.43) for elective cesarean section (ElCS) and 1.47 (95% CI: 1.33-1.62) for emergency cesarean section (EmCS). CONCLUSION: This meta-analysis suggests that CS and EmCS increase the risk of PPD. Further evidence is needed to explore the associations between the specific types of CS and the risk of PPD.
OBJECTIVE: The association of cesarean section (CS) with the risk of postpartum depression (PPD) remains controversial. Therefore, we conducted a meta-analysis to explore the association between CS and the risk of PPD. METHODS: A systematic literature search was performed in PubMed, Web of Science and Embase databases for relevant articles up to November 2016. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated with fixed-effects model or random-effects model. RESULTS: A total of 28 studies from 27 articles involving 532,630 participants were included in this meta-analysis. The pooled OR of the association between CS and PPD risk was 1.26 (95% CI: 1.16-1.36). In subgroup analyses stratified by study design [cohort studies: (1.25, 95% CI: 1.10-1.41); case-control studies: (1.25, 95% CI: 1.00-1.56); cross-sectional studies: (1.44, 95% CI: 1.14-1.82)] and adjustment status of complications during pregnancy [adjusted for: (1.29, 95% CI: 1.12-1.48); not-adjusted for: (1.24, 95% CI: 1.13-1.36)], the above-mentioned associations remained consistent. The pooled ORs of PPD were 1.15 (95% CI: 0.92-1.43) for elective cesarean section (ElCS) and 1.47 (95% CI: 1.33-1.62) for emergency cesarean section (EmCS). CONCLUSION: This meta-analysis suggests that CS and EmCS increase the risk of PPD. Further evidence is needed to explore the associations between the specific types of CS and the risk of PPD.
Authors: Rebecca B Morse; Abigail C Bretzin; Silvia P Canelón; Bernadette A D'Alonzo; Andrea L C Schneider; Mary R Boland Journal: Appl Clin Inform Date: 2022-03-09 Impact factor: 2.342
Authors: Francisco Javier Riesco-González; Irene Antúnez-Calvente; Juana María Vázquez-Lara; Luciano Rodríguez-Díaz; Rocío Palomo-Gómez; Juan Gómez-Salgado; Juan Jesús García-Iglesias; Tesifón Parrón-Carreño; Francisco Javier Fernández-Carrasco Journal: Medicina (Kaunas) Date: 2022-05-31 Impact factor: 2.948