Literature DB >> 28605638

Deriving, regenerating, and engineering CNS tissues using human pluripotent stem cells.

Kristen A Lemke1, Alireza Aghayee2, Randolph S Ashton3.   

Abstract

Progress in deriving a spectrum of central nervous system cell phenotypes from human pluripotent stem cells has spurred significant advances in in vitro modeling and development of regenerative therapies for neurological disorders. While the clinical impact of these advances is still being evaluated, their integration with advanced tissue engineering methodologies and therapeutic approaches that induce neural circuit plasticity, respectively, remain underexplored frontiers.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28605638      PMCID: PMC5617772          DOI: 10.1016/j.copbio.2017.05.010

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  53 in total

1.  Self-formation of optic cups and storable stratified neural retina from human ESCs.

Authors:  Tokushige Nakano; Satoshi Ando; Nozomu Takata; Masako Kawada; Keiko Muguruma; Kiyotoshi Sekiguchi; Koichi Saito; Shigenobu Yonemura; Mototsugu Eiraku; Yoshiki Sasai
Journal:  Cell Stem Cell       Date:  2012-06-14       Impact factor: 24.633

2.  Neural tube morphogenesis in synthetic 3D microenvironments.

Authors:  Adrian Ranga; Mehmet Girgin; Andrea Meinhardt; Dominic Eberle; Massimiliano Caiazzo; Elly M Tanaka; Matthias P Lutolf
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-14       Impact factor: 11.205

3.  Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.

Authors:  Lixiang Ma; Baoyang Hu; Yan Liu; Scott Christopher Vermilyea; Huisheng Liu; Lu Gao; Yan Sun; Xiaoqing Zhang; Su-Chun Zhang
Journal:  Cell Stem Cell       Date:  2012-03-15       Impact factor: 24.633

4.  Modeling familial Alzheimer's disease with induced pluripotent stem cells.

Authors:  Takuya Yagi; Daisuke Ito; Yohei Okada; Wado Akamatsu; Yoshihiro Nihei; Takahito Yoshizaki; Shinya Yamanaka; Hideyuki Okano; Norihiro Suzuki
Journal:  Hum Mol Genet       Date:  2011-09-07       Impact factor: 6.150

5.  Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation.

Authors:  Gabriel I Nistor; Minodora O Totoiu; Nadia Haque; Melissa K Carpenter; Hans S Keirstead
Journal:  Glia       Date:  2005-02       Impact factor: 7.452

6.  Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells.

Authors:  Ningzhe Zhang; Mahru C An; Daniel Montoro; Lisa M Ellerby
Journal:  PLoS Curr       Date:  2010-10-28

7.  Induced pluripotent stem cells from a spinal muscular atrophy patient.

Authors:  Allison D Ebert; Junying Yu; Ferrill F Rose; Virginia B Mattis; Christian L Lorson; James A Thomson; Clive N Svendsen
Journal:  Nature       Date:  2008-12-21       Impact factor: 49.962

8.  Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.

Authors:  Xuyu Qian; Ha Nam Nguyen; Mingxi M Song; Christopher Hadiono; Sarah C Ogden; Christy Hammack; Bing Yao; Gregory R Hamersky; Fadi Jacob; Chun Zhong; Ki-Jun Yoon; William Jeang; Li Lin; Yujing Li; Jai Thakor; Daniel A Berg; Ce Zhang; Eunchai Kang; Michael Chickering; David Nauen; Cheng-Ying Ho; Zhexing Wen; Kimberly M Christian; Pei-Yong Shi; Brady J Maher; Hao Wu; Peng Jin; Hengli Tang; Hongjun Song; Guo-Li Ming
Journal:  Cell       Date:  2016-04-22       Impact factor: 41.582

9.  Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.

Authors:  Stuart M Chambers; Yuchen Qi; Yvonne Mica; Gabsang Lee; Xin-Jun Zhang; Lei Niu; James Bilsland; Lishuang Cao; Edward Stevens; Paul Whiting; Song-Hai Shi; Lorenz Studer
Journal:  Nat Biotechnol       Date:  2012-07-01       Impact factor: 54.908

10.  Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model.

Authors:  Monica Nizzardo; Chiara Simone; Federica Rizzo; Margherita Ruggieri; Sabrina Salani; Giulietta Riboldi; Irene Faravelli; Chiara Zanetta; Nereo Bresolin; Giacomo P Comi; Stefania Corti
Journal:  Hum Mol Genet       Date:  2013-09-04       Impact factor: 6.150

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  2 in total

1.  Single-injection ex ovo transplantation method for broad spinal cord engraftment of human pluripotent stem cell-derived motor neurons.

Authors:  Maria C Estevez-Silva; Akshitha Sreeram; Stephanie Cuskey; Nikolai Fedorchak; Nisha Iyer; Randolph S Ashton
Journal:  J Neurosci Methods       Date:  2018-02-03       Impact factor: 2.390

Review 2.  Nanomaterial-Based Approaches for Neural Regeneration.

Authors:  Raluca Ioana Teleanu; Oana Gherasim; Tudor George Gherasim; Valentina Grumezescu; Alexandru Mihai Grumezescu; Daniel Mihai Teleanu
Journal:  Pharmaceutics       Date:  2019-06-08       Impact factor: 6.321

  2 in total

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