| Literature DB >> 28602465 |
Mehida Alexandre1, Jonathan Black2, Margaret Whicker1, Mary Jane Minkin1, Elena Ratner1.
Abstract
"Previvors", or "pre-survivors", are individuals who do not have cancer but have a genetic predisposition to cancer. One such example is women with BRCA mutations. As a result of their predisposition to cancer, many will undergo a bilateral salpingo-oophorectomy when they are premenopausal. For premenopausal women, the removal of ovaries results in the depletion of estrogen, immediate menopause, and, in many cases, resultant Sexuality, Intimacy, and Menopausal Symptoms (SIMS). Furthermore, they may undergo changes in body image. SIMS are underreported by patients and underdiagnosed by practitioners. At the time of diagnosis or at preoperative visits, women should be informed of the potential physiologic, hormonal, and psychosocial effects of their risk-reducing surgery. There are many modalities for management of these symptoms. Successful treatment requires the provider's awareness of the problem, ability to identify it, and willingness to treat it.Entities:
Keywords: Hormone replacement; Intimacy; Menopause; Ovarian cancer; Previvors; Risk reduction; Sexuality
Mesh:
Year: 2017 PMID: 28602465 DOI: 10.1016/j.maturitas.2017.06.003
Source DB: PubMed Journal: Maturitas ISSN: 0378-5122 Impact factor: 4.342