Literature DB >> 28602153

Frailty as a predictor of mortality in the elderly emergency general surgery patient.

Jens Goeteyn1, Louis A Evans2, Siem De Cleyn1, Sigrid Fauconnier1, Caroline Damen1, Jonathan Hewitt3, Wim Ceelen1.   

Abstract

BACKGROUND: The number of surgical procedures performed in elderly and frail patients has greatly increased in the last decades. However, there is little research in the elderly emergency general surgery patient. The aim of this study was to assess the prevalence of frailty in the emergency general surgery population in Belgium. Secondly, we examined the length of hospital stay, readmission rate and mortality at 30 and 90 days.
METHODS: We conducted a prospective observational study at Ghent University Hospital. All patients older than 65 admitted to a general surgery ward from the emergency department were eligible for inclusion. Primary endpoint was mortality at 30 days. Secondary outcomes were mortality at 90 days, readmissions and length of stay. Cross-sectional observations were performed using the Fisher exact test, Mann-Whitney U-test, or one-way ANOVA. We performed a COX multivariable analysis to identify independent variables associated with mortality at 30 and 90 days as well as the readmission risk.
RESULTS: Data were collected from 98 patients in a four-month period. 23.5% of patients were deemed frail. 79% of all patients underwent abdominal surgery. Univariate analyses showed that polypharmacy, multimorbidity, a history of falls, hearing impairment and urinary incontinence were statistically significantly different between the non-frail and the group. Frail patients showed a higher incidence for mortality within 30 days (9% versus 1.3% (p = .053)). There were no differences between the two groups for mortality at 90 days, readmission, length of stay and operation. Frailty was a predictor for mortality at 90 days (p= .025) (hazard ratio (HR) 10.83 (95%CI 1.34-87.4)). Operation (p= .084) (HR 0.16 (95%CI 0.16-1.29)) and the presence of chronic cardiac failure (p= .049) (HR 0.38 (95%CI 0.14-0.99)) were protective for mortality at 90 days.
CONCLUSION: Frailty is a significant predictor for mortality for elderly patients undergoing emergency abdominal/general surgery. LEVEL OF EVIDENCE: Level II therapeutic study.

Entities:  

Keywords:  Elderly patient; acute abdominal surgery; frailty; mortality; readmission

Mesh:

Year:  2017        PMID: 28602153     DOI: 10.1080/00015458.2017.1337339

Source DB:  PubMed          Journal:  Acta Chir Belg        ISSN: 0001-5458            Impact factor:   1.090


  10 in total

1.  Heath status, frailty, and multimorbidity in patients with emergency general surgery conditions.

Authors:  Vanessa P Ho; Wyatt P Bensken; Heena P Santry; Christopher W Towe; David F Warner; Alfred F Connors; Siran M Koroukian
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2.  The prevalence of frailty and post-treatment outcomes in elderly women with pelvic floor disorders.

Authors:  Kelly de Jong; Matthieu Y van der Vlist; Daniëlla M J Oom
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3.  Early Postoperative Death in Patients Undergoing Emergency High-Risk Surgery: Towards a Better Understanding of Patients for Whom Surgery May Not Be Beneficial.

Authors:  Geeta Aggarwal; Katherine J Broughton; Linda J Williams; Carol J Peden; Nial Quiney
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4.  Developing and validating a model for predicting 7-day mortality of patients admitted from the emergency department: an initial alarm score by a prospective prediction model study.

Authors:  Nin-Chieh Hsu; Chin-Chung Shu; Ming-Ju Hsieh; Yu-Feng Lin; Wen-Chu Chiang; Matthew Huei-Ming Ma; Wang-Huei Sheng
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6.  Frailty and Emergency Surgery: Results of a Systematic Review and Meta-Analysis.

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7.  Frailty and functional decline after emergency abdominal surgery in the elderly: a prospective cohort study.

Authors:  Hwee Leong Tan; Shermain Theng Xin Chia; Nivedita Vikas Nadkarni; Shin Yuh Ang; Dennis Chuen Chai Seow; Ting Hway Wong
Journal:  World J Emerg Surg       Date:  2019-12-30       Impact factor: 5.469

8.  Comparison of three frailty measures for 90-day outcomes of elderly patients undergoing elective abdominal surgery.

Authors:  Yanyan Yin; Li Jiang; Lixin Xue
Journal:  ANZ J Surg       Date:  2020-10-05       Impact factor: 1.872

9.  Association of Preoperative Risk Factors and Mortality in Older Patients following Emergency Abdominal Surgery: A Retrospective Cohort Study.

Authors:  Nadir Adnan Hacım; Ahmet Akbaş; Yigit Ulgen; Talar Vartanoglu Aktokmakyan; Serhat Meric; Merve Tokocin; Onder Karabay; Gulcin Ercan; Yuksel Altinel
Journal:  Ann Geriatr Med Res       Date:  2021-12-07

10.  Frailty in elderly patients with acute appendicitis.

Authors:  Alexander Reinisch; Martin Reichert; Christian Charles Ondo Meva; Winfried Padberg; Frank Ulrich; Juliane Liese
Journal:  Eur J Trauma Emerg Surg       Date:  2022-02-02       Impact factor: 2.374

  10 in total

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