Fabio Zaina1, Francesca Pesenti2, Luca Persani2,3, Paolo Capodaglio4, Stefano Negrini5,6, Nicoletta Polli2,3. 1. ISICO (Italian Scientific Spine Institute), Via Roberto Bellarmino 13/1, 20141, Milan, MI, Italy. fabio.zaina@isico.it. 2. Division of Eating Disorders, IRCCS Istituto Auxologico Italiano, 20149, Milan, MI, Italy. 3. Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, MI, Italy. 4. Rehabilitation Unit, Istituto Auxologico Italiano IRCCS, Piancavallo, VB, Italy. 5. Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. 6. IRCCS Don Gnocchi Foundation, Milan, Italy.
Abstract
PURPOSE: A long debate exists about the connection between anorexia nervosa (AN) and scoliosis due to conflicting evidence. No study so far has evaluated the prevalence of scoliosis in patients with AN. The aim of the study is to evaluate the prevalence of idiopathic scoliosis in patients with AN. METHODS: Design: cross-sectional study. STUDY GROUP: convenience sample of all patients matching the inclusion criteria. CONTROL GROUP: female participants coming from an epidemiological screening for scoliosis. INCLUSION CRITERIA: patients had a diagnosis of AN during adolescence according to the DSM-IV-TR criteria. We applied a two-level screening using a Bunnell scoliometer and a radiograph. We calculated the odds ratio compared with participants coming from a school screening. RESULTS: Seventy-seven females with AN were compared to 816 females screened for scoliosis. The prevalence of scoliosis in the AN group was 16.9% (OR 5.77, 95% CI 3.12-10.67) with respect to the control group. If we consider as positive only those who received a scoliosis diagnosis during adolescence, the OR would be 3.15 (95% CI 1.55-6.42). DISCUSSION: This is the first study performed on patients with AN showing a sixfold greater odds of presenting with scoliosis. A cause-effect relationship cannot be determined due to the design.
PURPOSE: A long debate exists about the connection between anorexia nervosa (AN) and scoliosis due to conflicting evidence. No study so far has evaluated the prevalence of scoliosis in patients with AN. The aim of the study is to evaluate the prevalence of idiopathic scoliosis in patients with AN. METHODS: Design: cross-sectional study. STUDY GROUP: convenience sample of all patients matching the inclusion criteria. CONTROL GROUP: female participants coming from an epidemiological screening for scoliosis. INCLUSION CRITERIA: patients had a diagnosis of AN during adolescence according to the DSM-IV-TR criteria. We applied a two-level screening using a Bunnell scoliometer and a radiograph. We calculated the odds ratio compared with participants coming from a school screening. RESULTS: Seventy-seven females with AN were compared to 816 females screened for scoliosis. The prevalence of scoliosis in the AN group was 16.9% (OR 5.77, 95% CI 3.12-10.67) with respect to the control group. If we consider as positive only those who received a scoliosis diagnosis during adolescence, the OR would be 3.15 (95% CI 1.55-6.42). DISCUSSION: This is the first study performed on patients with AN showing a sixfold greater odds of presenting with scoliosis. A cause-effect relationship cannot be determined due to the design.
Authors: Stuart L Weinstein; Lori A Dolan; Kevin F Spratt; Kirk K Peterson; Mark J Spoonamore; Ignacio V Ponseti Journal: JAMA Date: 2003-02-05 Impact factor: 56.272
Authors: Fabio Zaina; Sabrina Donzelli; Monia Lusini; Luca Vismara; Paolo Capodaglio; Laura Neri; Stefano Negrini Journal: Res Dev Disabil Date: 2013-01-28
Authors: Stefano Negrini; Angelo G Aulisa; Lorenzo Aulisa; Alin B Circo; Jean Claude de Mauroy; Jacek Durmala; Theodoros B Grivas; Patrick Knott; Tomasz Kotwicki; Toru Maruyama; Silvia Minozzi; Joseph P O'Brien; Dimitris Papadopoulos; Manuel Rigo; Charles H Rivard; Michele Romano; James H Wynne; Monica Villagrasa; Hans-Rudolf Weiss; Fabio Zaina Journal: Scoliosis Date: 2012-01-20
Authors: Elisa M S Tam; Fiona W P Yu; Vivian W Y Hung; Zhen Liu; King Lok Liu; Bobby K W Ng; Simon K M Lee; Yong Qiu; Jack C Y Cheng; Tsz-Ping Lam Journal: PLoS One Date: 2014-02-06 Impact factor: 3.240