| Literature DB >> 28601878 |
Sul A Lee, Sanjeev Noel, Mohanraj Sadasivam, Abdel R A Hamad, Hamid Rabb.
Abstract
Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of immune cells in the early injury and repair from AKI. In this brief review, we aim to update information on the pathophysiologic impact of various immune cells in AKI, with special emphasis on repair. An improved understanding of the AKI immunopathology will lead to new therapies that prevent AKI, accelerate repair, and prevent the progression of AKI to chronic kidney disease.Entities:
Keywords: Acute kidney injury; B lymphocyte; Dendritic cells; Double-negative T cells; Immune cells; Inflammation; Kidney repair; Macrophage; Neutrophil; Regulatory T cells; T lymphocyte
Mesh:
Year: 2017 PMID: 28601878 PMCID: PMC5723562 DOI: 10.1159/000477181
Source DB: PubMed Journal: Nephron ISSN: 1660-8151 Impact factor: 2.847