Literature DB >> 28600763

Mycobacterial Load Assay.

Stephen H Gillespie1, Wilber Sabiiti2, Katarina Oravcova2.   

Abstract

Tuberculosis is a difficult disease to treat, a process made more harder as tools to monitor treatment response only provide a result long after the patient has provided a sample. The mycobacterial load assay (MBLA) provides a simple molecular test to quantify and determine the viability of M. tuberculosis in human or other samples.

Entities:  

Keywords:  Mycobacterial load assay (MBLA); Reverse transcriptase real-time quantitative polymerase chain reaction (RT-qPCR); Ribosomal RNA (rRNA); Sputum

Mesh:

Year:  2017        PMID: 28600763     DOI: 10.1007/978-1-4939-7037-7_5

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  5 in total

1.  Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture.

Authors:  Robin J Svensson; Wilber Sabiiti; Gibson S Kibiki; Nyanda E Ntinginya; Nilesh Bhatt; Geraint Davies; Stephen H Gillespie; Ulrika S H Simonsson
Journal:  Antimicrob Agents Chemother       Date:  2019-09-23       Impact factor: 5.191

Review 2.  Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies.

Authors:  Jan Heyckendorf; Sophia B Georghiou; Nicole Frahm; Norbert Heinrich; Irina Kontsevaya; Maja Reimann; David Holtzman; Marjorie Imperial; Daniela M Cirillo; Stephen H Gillespie; Morten Ruhwald
Journal:  Clin Microbiol Rev       Date:  2022-03-21       Impact factor: 50.129

3.  Mycobactericidal Effects of Different Regimens Measured by Molecular Bacterial Load Assay among People Treated for Multidrug-Resistant Tuberculosis in Tanzania.

Authors:  Peter M Mbelele; Emmanuel A Mpolya; Elingarami Sauli; Bariki Mtafya; Nyanda E Ntinginya; Kennedy K Addo; Katharina Kreppel; Sayoki Mfinanga; Patrick P J Phillips; Stephen H Gillespie; Scott K Heysell; Wilber Sabiiti; Stellah G Mpagama
Journal:  J Clin Microbiol       Date:  2021-03-19       Impact factor: 5.948

4.  High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis.

Authors:  Emmanuel Musisi; Abdul Sessolo; Sylvia Kaswabuli; Josephine Zawedde; Patrick Byanyima; Shariifah Kasinga; Ingvar Sanyu; Esther Uwimaana; Stanley Walimbwa; Joseph Olore; Willy Ssengooba; Christine Sekaggya; Moses L Joloba; William Worodria; Laurence Huang; Stephen H Gillespie; Derek J Sloan; Wilber Sabiiti
Journal:  Microbiol Spectr       Date:  2022-01-12

5.  Detection and Quantification of Viable Mycobacterium tuberculosis Bacilli in Saline-Processed Stool Samples by Tuberculosis Molecular Bacterial Load Assay: a Potential Alternative for Processing Stool.

Authors:  Emmanuel Musisi; Abdul Ssesolo; Derek J Sloan; Stephen H Gillespie; Wilber Sabiiti
Journal:  Microbiol Spectr       Date:  2022-05-12
  5 in total

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