Literature DB >> 2860068

Vaccination of rabbits against Entamoeba histolytica with aqueous suspensions of trehalose-dimycolate as the adjuvant.

A Sharma, A Haq, S Ahmad, E Lederer.   

Abstract

Rabbits were immunized with soluble Entamoeba histolytica antigen with an aqueous suspension of trehalose-6,6'-dimycolate used as the adjuvant. Induction of protective immunity in the immunized animals was demonstrated by enhanced humoral and cell-mediated immune responses and 100% survival after challenge. Administration of soluble antigen only failed to induce a similar degree of protective immunity. Trehalose-6,6'-dimycolate alone produced only a slight increase in nonspecific resistance.

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Year:  1985        PMID： 2860068      PMCID： PMC261212          DOI： 10.1128/iai.48.3.634-637.1985

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  34 in total

1.  Cell-mediated immunity in patients with amebic abscess of the liver.

Authors:  L Ortiz-Ortiz; G Zamacona; B Sepúlveda; N R Capín
Journal:  Clin Immunol Immunopathol       Date:  1975-05

2.  Cord factor and related trehalose esters.

Authors:  E Lederer
Journal:  Chem Phys Lipids       Date:  1976-03       Impact factor: 3.329

3.  Cellular immune responses to amoebic liver abcess in the guinea-pig.

Authors:  R S Bray; W G Harris
Journal:  Clin Exp Immunol       Date:  1977-07       Impact factor: 4.330

4.  Behavior of axenic IP-106 strain of Entamoeba histolytica in the golden hamster.

Authors:  E Ghadirian; E Meerovitch
Journal:  Am J Trop Med Hyg       Date:  1978-03       Impact factor: 2.345

Review 5.  Trehalose-containing glycolipids.

Authors:  C Asselineau; J Asselineau
Journal:  Prog Chem Fats Other Lipids       Date:  1978

6.  Protective immunity to amebic infection demonstrated in guinea pigs.

Authors:  I M Krupp
Journal:  Am J Trop Med Hyg       Date:  1974-05       Impact factor: 2.345

7.  Induction of resistance to Schistosoma mansoni by natural cord factor and synthetic lower homologues.

Authors:  G R Olds; L Chedid; E Lederer; A A Mahmoud
Journal:  J Infect Dis       Date:  1980-04       Impact factor: 5.226

8.  Enhancement of nonspecific immunity to bacterial infection by cord factor (6,6'-trehalose dimycolate).

Authors:  M Parant; F Parant; L Chedid; J C Drapier; J F Petit; J Wietzerbin
Journal:  J Infect Dis       Date:  1977-05       Impact factor: 5.226

9.  The effect of Toxoplasma cell fractions and mycobacterial immunostimulants against virulent Toxoplasma gondii in mice.

Authors:  K N Masihi; W Brehmer; H Werner
Journal:  Zentralbl Bakteriol Orig A       Date:  1979

10.  Stimulation of thymocyte mitogenic protein secretion and of cytostatic activity of mouse peritoneal macrophages by trehalose dimycolate and muramyldipeptide.

Authors:  J P Tenu; E Lederer; J F Petit
Journal:  Eur J Immunol       Date:  1980-08       Impact factor: 5.532
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  5 in total

1.  Adjuvant effects of trehalose dimycolate on the antibody response to type III pneumococcal polysaccharide.

Authors:  P J Baker; M B Fauntleroy; P W Stashak; J R Hiernaux; J L Cantrell; J A Rudbach
Journal:  Infect Immun       Date:  1989-03       Impact factor: 3.441

2.  Protection of gerbils from amebic liver abscess by immunization with a recombinant protein derived from the 170-kilodalton surface adhesin of Entamoeba histolytica.

Authors:  T Zhang; S L Stanley
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

3.  Protection of gerbils from amebic liver abscess by immunization with the galactose-specific adherence lectin of Entamoeba histolytica.

Authors:  W A Petri; J I Ravdin
Journal:  Infect Immun       Date:  1991-01       Impact factor: 3.441

4.  Isolation of the galactose-binding lectin that mediates the in vitro adherence of Entamoeba histolytica.

Authors:  W A Petri; R D Smith; P H Schlesinger; C F Murphy; J I Ravdin
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

5.  Protection of gerbils from amebic liver abscess by immunization with a recombinant Entamoeba histolytica antigen.

Authors:  T Zhang; P R Cieslak; S L Stanley
Journal:  Infect Immun       Date:  1994-04       Impact factor: 3.441
  5 in total

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