| Literature DB >> 28599355 |
Yafan Yang1, Guiying Wang1, Jingli He1, Shuguang Ren2, Fengpeng Wu3, Jianfeng Zhang1, Feifei Wang1.
Abstract
A meta-analysis was conducted to determine the influence of gender on overall survival (OS) and cancer-specific survival (CSS) in colorectal cancer patients. Major databases were searched for clinical trials, which compare survival differences between male and female for colorectal cancer patients. A list of these studies and references, published in English and Chinese from 1960 to 2017, was obtained independently by two reviewers from databases such as PubMed, Medline, ScienceDirect, the China National Knowledge Infrastructure (CNKI) and Web of Science. Overall survival and cancer-specific survival were compared using Review Manager 5.3. Females had significantly better OS (hazard ratio [HR] = 0.87; 95% confidence interval [CI] = 0.85-0.89) and CSS (HR = 0.92; 95% CI = 0.89-0.95) than males after meta-analysis. These results suggest that gender seems to be a significant factor influencing survival results among colorectal cancer patients.Entities:
Keywords: CSS; OS; cancer-specific survival; colorectal cancer; gender; meta-analysis; overall survival
Mesh：
Year: 2017 PMID： 28599355 DOI： 10.1002/ijc.30827
Source DB: PubMed Journal: Int J Cancer ISSN： 0020-7136 Impact factor: 7.396