Literature DB >> 2859877

A double-blind comparison of alprazolam, diazepam and placebo in the treatment of anxious out-patients.

K Davison, R G Farquharson, M C Khan, A Majid.   

Abstract

In a double-blind 28-day comparison of alprazolam, diazepam and placebo, alprazolam 1.5-3 mg/day was of equivalent anxiolytic effect to 15-30 mg diazepam/day and there was some evidence of antidepressant activity by alprazolam, but not diazepam, in neurotic depression. No serious side-effects or laboratory abnormalities were encountered.

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Year:  1985        PMID: 2859877      PMCID: PMC1463497          DOI: 10.1111/j.1365-2125.1985.tb02741.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  6 in total

1.  Pilot open label study with alprazolam (U31, 889) in outpatients with neurotic depression.

Authors:  L F Fabre
Journal:  Curr Ther Res Clin Exp       Date:  1976-06

2.  The assessment of anxiety states by rating.

Authors:  M HAMILTON
Journal:  Br J Med Psychol       Date:  1959

3.  A rating scale for depression.

Authors:  M HAMILTON
Journal:  J Neurol Neurosurg Psychiatry       Date:  1960-02       Impact factor: 10.154

4.  Multicenter double-blind efficacy and safety study comparing alprazolam, diazepam and placebo in clinically anxious patients.

Authors:  J B Cohn
Journal:  J Clin Psychiatry       Date:  1981-09       Impact factor: 4.384

5.  Anxiolytic efficacy of alprazolam compared to diazepam and placebo.

Authors:  B M Maletzky
Journal:  J Int Med Res       Date:  1980       Impact factor: 1.671

6.  Alprazolam compared to diazepam and placebo in the treatment of anxiety.

Authors:  G C Aden; S G Thein
Journal:  J Clin Psychiatry       Date:  1980-07       Impact factor: 4.384

  6 in total
  1 in total

1.  The effects of triazolobenzodiazepines in two animal tests of anxiety and in the holeboard.

Authors:  S E File; S Pellow
Journal:  Br J Pharmacol       Date:  1985-11       Impact factor: 8.739

  1 in total

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