Literature DB >> 28596229

Implementation of a proton pump inhibitor stewardship program.

Kelly W Davis1, Rachel E Hanners2, Sean M Lockwood2.   

Abstract

PURPOSE: The development and implementation of a proton pump inhibitor (PPI) stewardship program at a single institution are described.
SUMMARY: Due to the overuse of PPIs and the increasing awareness of the adverse drug events associated with long-term PPI therapy, the pharmacy and internal medicine services of a medical center implemented a PPI stewardship program. All patients admitted to the internal medicine service were evaluated by the PPI stewardship team to determine if they had an appropriate indication for PPI continuation in the hospital as well as after discharge. If patients did not meet specified criteria for continuation of PPI use during hospitalization, PPI therapy was suspended and replaced by as-needed acid suppressive therapy, and the patients received discharge counseling regarding the implemented medication regimen changes. Challenges encountered during program development included establishing appropriate criteria for PPI continuation and determining the best method for discontinuing PPIs in order to reduce the risk of rebound hyperacidity.
CONCLUSION: In an effort to reduce unnecessary PPI use, a PPI stewardship program was developed and implemented to ensure appropriate continuation of PPIs for patients admitted and discharged from an internal medicine service.
Copyright © 2017 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Entities:  

Keywords:  antacids; anti-ulcer agents; gastric acid; gastroesophageal reflux; gastrointestinal tract; proton pump inhibitor

Mesh:

Substances:

Year:  2017        PMID: 28596229     DOI: 10.2146/ajhp160670

Source DB:  PubMed          Journal:  Am J Health Syst Pharm        ISSN: 1079-2082            Impact factor:   2.637


  3 in total

1.  Outcomes From a Pharmacist - led Proton Pump Inhibitor Stewardship Program at a Single Institution.

Authors:  Rebekah A Wahking; Randal L Steele; Rachel E Hanners; Sean M Lockwood; Kelly W Davis
Journal:  Hosp Pharm       Date:  2017-12-13

2.  Use and prescription appropriateness of drugs for peptic ulcer and gastrooesophageal reflux disease in hospitalized older people.

Authors:  C Franchi; P M Mannucci; A Nobili; I Ardoino
Journal:  Eur J Clin Pharmacol       Date:  2019-12-18       Impact factor: 2.953

3.  Patients, Prescribers, and Institutional Factors Associated with Inappropriate Use of Acid Suppressive Therapy in Medical Wards: An Experience of a Single-Center in Saudi Arabia.

Authors:  Ghazwa B Korayem; Raghad Alkanhal; Raghad Almass; Sarah Alkhunaizan; Ghada Alharthi; Nader Bin Sheraim; Sara Alqahtani; Hadeel Alkofide
Journal:  Int J Gen Med       Date:  2021-08-30
  3 in total

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