| Literature DB >> 28596002 |
Helena Ban Frangez1, Sara Korošec2, Barbara Pozlep2, Nina Jancar2, Vesna Salamun2, Andrej Vogler2, Tanja Burnik Papler2, Tea Terezija Cvetko2, Eda Vrtacnik Bokal2.
Abstract
With the development of IVF procedures, the role of reproductive surgery in the management of infertile couples has been questioned. Pregnancy rates (PR) after IVF procedures are well known, but recent data on spontaneous PR after reproductive surgery are scarce. This study aimed to prospectively evaluate how often fertility is restored by reproductive surgery and to identify which independent factors influence spontaneous pregnancy after reproductive surgery. Eight hundred eighty-eight infertile women who underwent surgery for infertility were prospectively included. Women who were referred to IVF after surgery, ceased to plan pregnancy and were lost to follow-up were excluded. Spontaneous PR was analysed for 519 women. A total of 252 (48.6%) women, including 30 treated with clomiphene citrate, conceived spontaneously in the 12-18 months observation period following surgery. Multivariate logistic regression showed that woman's age (OR 0.95, 95% CI 0.90-0.99) and duration of infertility (OR 0.86, 95% CI 0.74-0.99) significantly influence spontaneous PR. Each year of infertility lowers spontaneous PR following surgery by 14% and each year of woman's age by 5%. The study shows a relatively high percentage of women conceived spontaneously after reproductive surgery. The role of reproductive surgery in the management of infertility should be re-evaluated.Entities:
Keywords: IVF; Infertility; Reproductive surgery; Spontaneous pregnancy
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Year: 2017 PMID: 28596002 DOI: 10.1016/j.rbmo.2017.05.007
Source DB: PubMed Journal: Reprod Biomed Online ISSN: 1472-6483 Impact factor: 3.828