Literature DB >> 28596002

Spontaneous pregnancy rates after reproductive surgery.

Helena Ban Frangez1, Sara Korošec2, Barbara Pozlep2, Nina Jancar2, Vesna Salamun2, Andrej Vogler2, Tanja Burnik Papler2, Tea Terezija Cvetko2, Eda Vrtacnik Bokal2.   

Abstract

With the development of IVF procedures, the role of reproductive surgery in the management of infertile couples has been questioned. Pregnancy rates (PR) after IVF procedures are well known, but recent data on spontaneous PR after reproductive surgery are scarce. This study aimed to prospectively evaluate how often fertility is restored by reproductive surgery and to identify which independent factors influence spontaneous pregnancy after reproductive surgery. Eight hundred eighty-eight infertile women who underwent surgery for infertility were prospectively included. Women who were referred to IVF after surgery, ceased to plan pregnancy and were lost to follow-up were excluded. Spontaneous PR was analysed for 519 women. A total of 252 (48.6%) women, including 30 treated with clomiphene citrate, conceived spontaneously in the 12-18 months observation period following surgery. Multivariate logistic regression showed that woman's age (OR 0.95, 95% CI 0.90-0.99) and duration of infertility (OR 0.86, 95% CI 0.74-0.99) significantly influence spontaneous PR. Each year of infertility lowers spontaneous PR following surgery by 14% and each year of woman's age by 5%. The study shows a relatively high percentage of women conceived spontaneously after reproductive surgery. The role of reproductive surgery in the management of infertility should be re-evaluated.
Copyright © 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  IVF; Infertility; Reproductive surgery; Spontaneous pregnancy

Mesh:

Substances:

Year:  2017        PMID: 28596002     DOI: 10.1016/j.rbmo.2017.05.007

Source DB:  PubMed          Journal:  Reprod Biomed Online        ISSN: 1472-6483            Impact factor:   3.828


  3 in total

Review 1.  Spontaneous pregnancies and determinant factors in infertility: A cross-sectional study.

Authors:  Nasrin Saadati; Roshan Nikbakht; Alireza Sattari; Fatemeh Sadat Amininezhad
Journal:  Int J Reprod Biomed       Date:  2020-10-13

2.  Deep Infiltrating Endometriosis: a Previous History of Surgery for Endometriosis May Negatively Affect Assisted Reproductive Technology Outcomes.

Authors:  Chloé Maignien; Pietro Santulli; Mathilde Bourdon; Diane Korb; Louis Marcellin; Marie-Charlotte Lamau; Charles Chapron
Journal:  Reprod Sci       Date:  2020-01-06       Impact factor: 3.060

3.  Is IVF/ICSI [corrected] an Independent Risk Factor for Spontaneous Preterm Birth in Singletons? A Population-Based Cohort Study.

Authors:  Nina Jančar; Barbara Mihevc Ponikvar; Sonja Tomšič; Eda Vrtačnik Bokal; Sara Korošec
Journal:  Biomed Res Int       Date:  2018-12-30       Impact factor: 3.411

  3 in total

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