| Literature DB >> 28595726 |
Xiaoling Zheng1, Ruixue Ji1, Xiaoqun Cao1, Yanqing Ge2.
Abstract
A new fluorophore indolizine was synthesized and used as a donor to construct FRET system. The chemodosimeter shows a large Stokes shifts (193 nm), high sensitivity, and high selectivity. The probe can quickly (10 min) detect Cu2+ effectively in a wide pH range from 5 to 12 and with a detection limit as low as 9.1 × 10-9 M. Furthermore, it could be used for imaging Cu2+ in living Glioma cells which demonstrated its value of practical applications in biological systems.Entities:
Keywords: Bioimaging; Cu(2+); FRET; Fluorescent probe; Indolizine
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Year: 2017 PMID: 28595726 DOI: 10.1016/j.aca.2017.04.048
Source DB: PubMed Journal: Anal Chim Acta ISSN: 0003-2670 Impact factor: 6.558