Jaap Swanenburg1,2,3, Aron Zurbrugg1,4, Dominik Straumann5, Stefan C A Hegemann6, Antonella Palla5, Eling D de Bruin4,7,8. 1. a Physiotherapy and Occupational Therapy Research , University Hospital Zurich , Zurich , Switzerland. 2. b Department of Physiotherapy , Balgrist University Hospital , Zurich , Switzerland. 3. c Department of Chiropractic Medicine , Balgrist University Hospital , Zürich , Switzerland. 4. d Department Health Sciences and Technology , Institute of Human Movement Sciences and Sport, ETH Zurich , Zurich , Switzerland. 5. e Department of Neurology , University Hospital Zurich , Zurich , Switzerland. 6. f Department of Otorhinolaryngology , Head and Neck Surgery, and Zurich Center for Integrative Human Physiology , Zurich , Switzerland. 7. g Department of Epidemiology, CAPHRI School for Public Health and Primary Care , Maastricht University , Maastricht , The Netherlands. 8. h Centre for Evidence Based Physiotherapy , Maastricht University , Maastricht , The Netherlands.
Abstract
BACKGROUND: This study aimed to analyze the association between prospectively assessed falls and functional abilities in patients with bilateral vestibulopathy (BVP). METHODS: Nineteen BVP patients had functional abilities assessed at baseline with the expanded timed get-up-and-go (ETGUG) test. Falls were prospectively recorded with a monthly "fall calendar" over a one-year period. Association between baseline functional abilities and falls was evaluated by Mann-Whitney U testing. Logistic regression was applied to describe the relationship between falls and functional abilities. Area under the receiver-operating characteristic curve (AUC) was used predicting falls based on gait speed. RESULTS: Eight (45%) of 18 patients (61.11 ± 15.19 years, 12 male) reported 19 falls. Fallers had a significantly faster preferred gait speed (p = 0.03) in the fifth component of the ETGUG. Preferred gait speed was a significant factor in the prediction of falls model (odds ratio = 2.00, p = 0.05, CI = 1.00/4.00 per 10 cm/s). ACU was 0.80 and the cutoff score of 1.35m/s (sensitivity = 75%, specificity = 70%) in predicting falls. DISCUSSION: BVP patients classified as fallers demonstrated significant faster gait speed after a turning maneuver. Future studies in larger BVP patient samples are needed to refute or confirm our findings.
BACKGROUND: This study aimed to analyze the association between prospectively assessed falls and functional abilities in patients with bilateral vestibulopathy (BVP). METHODS: Nineteen BVP patients had functional abilities assessed at baseline with the expanded timed get-up-and-go (ETGUG) test. Falls were prospectively recorded with a monthly "fall calendar" over a one-year period. Association between baseline functional abilities and falls was evaluated by Mann-Whitney U testing. Logistic regression was applied to describe the relationship between falls and functional abilities. Area under the receiver-operating characteristic curve (AUC) was used predicting falls based on gait speed. RESULTS: Eight (45%) of 18 patients (61.11 ± 15.19 years, 12 male) reported 19 falls. Fallers had a significantly faster preferred gait speed (p = 0.03) in the fifth component of the ETGUG. Preferred gait speed was a significant factor in the prediction of falls model (odds ratio = 2.00, p = 0.05, CI = 1.00/4.00 per 10 cm/s). ACU was 0.80 and the cutoff score of 1.35m/s (sensitivity = 75%, specificity = 70%) in predicting falls. DISCUSSION: BVP patients classified as fallers demonstrated significant faster gait speed after a turning maneuver. Future studies in larger BVP patient samples are needed to refute or confirm our findings.
Entities:
Keywords:
Falls; gait; prospective; validity; vestibular loss
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