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Literature DB >> 28594265

β cell self-renewal: Cyclin D2 to the rescue.

Naureen Javeed¹, Aleksey V Matveyenko¹.

Abstract

Entities: Gene

Mesh：

Substances：
Cyclin D2

Year: 2017 PMID： 28594265 PMCID： PMC5539820 DOI： 10.1080/15384101.2017.1337988

Source DB: PubMed Journal: Cell Cycle ISSN： 1551-4005 Impact factor: 4.534

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7 in total

Review 1. The replication of beta cells in normal physiology, in disease and for therapy.

Authors: Peter C Butler; Juris J Meier; Alexandra E Butler; Anil Bhushan
Journal: Nat Clin Pract Endocrinol Metab Date: 2007-11

2. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

Authors: Senta Georgia; Anil Bhushan
Journal: J Clin Invest Date: 2004-10 Impact factor: 14.808

3. Human β-cell proliferation and intracellular signaling: driving in the dark without a road map.

Authors: Rohit N Kulkarni; Ernesto-Bernal Mizrachi; Adolfo Garcia Ocana; Andrew F Stewart
Journal: Diabetes Date: 2012-06-29 Impact factor: 9.461

4. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Authors: Peng Wang; Juan-Carlos Alvarez-Perez; Dan P Felsenfeld; Hongtao Liu; Sharmila Sivendran; Aaron Bender; Anil Kumar; Roberto Sanchez; Donald K Scott; Adolfo Garcia-Ocaña; Andrew F Stewart
Journal: Nat Med Date: 2015-03-09 Impact factor: 53.440

β cell self-renewal: Cyclin D2 to the rescue.

Review 1. The replication of beta cells in normal physiology, in disease and for therapy.

2. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

3. Human β-cell proliferation and intracellular signaling: driving in the dark without a road map.

4. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

5. Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents.

6. The Genetic Program of Pancreatic β-Cell Replication In Vivo.

7. Cyclin D2 is sufficient to drive β cell self-renewal and regeneration.