Literature DB >> 2859361

Gamma-glutamyl transpeptidase activity and its serial measurement in differentiation between extrahepatic biliary atresia and neonatal hepatitis.

K P Fung, S P Lau.   

Abstract

The liver functions of 17 babies with extrahepatic biliary atresia (EHBA) and 19 babies with neonatal hepatitis (NNH) were analyzed. The serum gamma-glutamyl transpeptidase (GGTP) level and its rate of rise were significantly higher in the EHBA group. Both cross-sectional and longitudinal studies showed a positive correlation between the GGTP activity and the duration of the disease. The diagnostic accuracy is 79% for EHBA and 95% for NNH. It is suggested that GGTP and its rate of rise are the most important biochemical parameters in the differential diagnosis of these two diseases.

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Year:  1985        PMID： 2859361     DOI： 10.1097/00005176-198504000-00009

Source DB:  PubMed          Journal:  J Pediatr Gastroenterol Nutr        ISSN： 0277-2116            Impact factor:   2.839


  3 in total

1.  Lipoprotein-X and diagnosis of biliary atresia.

Authors:  K P Fung
Journal:  Eur J Pediatr       Date:  1987-05       Impact factor: 3.183

2.  Significance of serum lipoprotein-X and gammaglutamyltranspeptidase in the diagnosis of biliary atresia. A preliminary study in 27 cholestatic young infants.

Authors:  Y Tazawa; M Yamada; M Nakagawa; K Tada; T Konno; R Ohi; M Kasai
Journal:  Eur J Pediatr       Date:  1986-04       Impact factor: 3.183

3.  The utility of shear wave elastography and serum biomarkers for diagnosing biliary atresia and predicting clinical outcomes.

Authors:  Yakun Liu; Chunhui Peng; Kai Wang; Dongyang Wu; Jun Yan; Wenjun Tu; Yajun Chen
Journal:  Eur J Pediatr       Date:  2021-06-30       Impact factor: 3.183
  3 in total

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