Literature DB >> 28591939

Current and future therapies for advanced pancreatic cancer.

Rohan Gupta1, Idoroenyi Amanam1, Vincent Chung1.   

Abstract

Pancreatic cancer remains a deadly disease with a 5-year survival rate of only 8%. Even after surgical resection, most patients have recurrence of their cancer. Over the last 10 years, improvements in chemotherapy regimens led to a doubling in median overall survival. Here we review the management of advanced pancreatic cancer and highlight vaccine therapy as a novel modality of treatment.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  cytotoxic chemotherapy; pancreas cancer; vaccine therapy

Mesh：

Substances：

Year:  2017        PMID： 28591939     DOI： 10.1002/jso.24623

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  40 in total

1.  Cytoreduction with Hyperthermic Intraperitoneal Chemoperfusion for Pancreatic Cancer with Low-Volume Peritoneal Metastasis: Results from a Prospective Pilot Study.

Authors:  Travis E Grotz; Jennifer A Yonkus; Cornelius A Thiels; Susanne G Warner; Robert R McWilliams; Amit Mahipal; Tanios S Bekaii-Saab; Sean P Cleary; Michael L Kendrick; Mark J Truty
Journal:  Ann Surg Oncol       Date:  2022-08-16       Impact factor: 4.339

Review 2.  Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival.

Authors:  Mark B Ulanja; Alastair E Moody; Bryce D Beutler; Daniel Antwi-Amoabeng; Ganiyu A Rahman; Olatunji B Alese
Journal:  Oncotarget       Date:  2022-06-15

3.  Deoxyelephantopin Suppresses Pancreatic Cancer Progression In Vitro and In Vivo by Targeting linc00511/miR-370-5p/p21 Promoter Axis.

Authors:  Daolin Ji; Li Hou; Chunyang Xie; Haonan Feng; Dongdong Bao; Yue Teng; Junhao Liu; Tiangang Cui; Xiuhong Wang; Yi Xu; Gang Tan
Journal:  J Oncol       Date:  2022-06-25       Impact factor: 4.501

4.  SIRT6 promotes ferroptosis and attenuates glycolysis in pancreatic cancer through regulation of the NF-κB pathway.

Authors:  Shuangxi Gong; Lixin Xiong; Zhen Luo; Qinghua Yin; Ming Huang; Yang Zhou; Jian Li
Journal:  Exp Ther Med       Date:  2022-06-08       Impact factor: 2.751

Review 5.  Pancreatic Cancer: An Emphasis on Current Perspectives in Immunotherapy.

Authors:  Krishna Patel; Sohail Siraj; Chloe Smith; Maya Nair; Jamboor K Vishwanatha; Riyaz Basha
Journal:  Crit Rev Oncog       Date:  2019

6.  Impact of surveillance among patients with resected pancreatic cancer following adjuvant chemotherapy.

Authors:  Selina K Wong; Lovedeep Gondara; Daniel J Renouf; Howard J Lim; Jonathan M Loree; Janine M Davies; Sharlene Gill
Journal:  J Gastrointest Oncol       Date:  2021-04

7.  Impact of PET/MRI in the Treatment of Pancreatic Adenocarcinoma: a Retrospective Cohort Study.

Authors:  Felipe S Furtado; Cristina R Ferrone; Susanna I Lee; Mark Vangel; David A Rosman; Colin Weekes; Motaz Qadan; Carlos Fernandez-Del Castillo; David P Ryan; Lawrence S Blaszkowsky; Theodore S Hong; Jeffrey W Clark; Robin Striar; David Groshar; Lina G Cañamaque; Lale Umutlu; Onofrio A Catalano
Journal:  Mol Imaging Biol       Date:  2021-01-07       Impact factor: 3.488

Review 8.  Glutathione S-Transferases in Cancer.

Authors:  Rahul Raj Singh; Katie M Reindl
Journal:  Antioxidants (Basel)       Date:  2021-04-29

9.  Inhibition of de novo pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer.

Authors:  Thuy Phan; Vu H Nguyen; Ralf Buettner; Corey Morales; Lifeng Yang; Paul Wong; Weiman Tsai; Marcela d'Alincourt Salazar; Ziv Gil; Don J Diamond; Joshua D Rabinowitz; Steven Rosen; Laleh G Melstrom
Journal:  Int J Biol Sci       Date:  2021-06-01       Impact factor: 6.580

Review 10.  Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer.

Authors:  Ramiz S Ahmad; Timothy D Eubank; Slawomir Lukomski; Brian A Boone
Journal:  Biomolecules       Date:  2021-06-17
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