| Literature DB >> 28589738 |
Rayra P Santiago1,2, Rodrigo M Oliveira1,2, Leonardo F Soares3, Camylla V B Figueiredo1,2, Denise Oliveira Silva4, Ana F Hurtado-Guerrero4, Luciana M Fiuza1,2, Caroline C Guarda1,2, Elisângela V Adorno2, Cynara G Barbosa2, Marilda S Gonçalves1,2.
Abstract
Brazilian Quilombolas are communities composed of African-derived populations that have their territories guaranteed by the Brazilian Constitution. The present study investigated the hemoglobin (Hb) variants among these population groups. This study was conducted in a total of 2843 individuals of Brazilian Quilombola communities of the Bahia, Pará, and Piauí states. All the participants had their Hb profiles evaluated. The Hb S (HBB: c.20A>T) variant was described in all the studied localities. However, the individuals in Bahia State had the highest frequency of the Hb C (HBB: c.19G>A) variant; individuals from Piauí State had a higher frequency of the Hb D-Punjab (HBB: c.364G>C) variant compared to the other states, and individuals from Pará State only carried the Hb S variant. The present study revealed a specific distribution of Hb variants that could represent different waves of African influence in these Brazilian populations.Entities:
Keywords: Africans; Quilombola; hemoglobin (Hb) variant; hemoglobinopathy
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Year: 2017 PMID： 28589738 DOI： 10.1080/03630269.2017.1321014
Source DB: PubMed Journal: Hemoglobin ISSN： 0363-0269 Impact factor: 0.849