Literature DB >> 2858871

The D1 dopamine receptor antagonist, SCH 23390 reduces locomotor activity and rearing in rats.

D C Hoffman, R J Beninger.   

Abstract

Dopamine receptors have been found to be of at least two types, and interest has focused on the possible differential role played by each in the control of behavior. The recent finding that SCH 23390 selectively blocks D1 receptors has provided a new tool. To examine the contribution of D1 receptors to locomotor activity and rearing, rats were injected SC with doses of 0.01, 0.1 and 1.0 mg/kg and monitored for 3 hr in photocell cages. SCH 23390 suppressed both behaviors in a dose-dependent fashion. These results suggest that D1 receptors participate in dopamine's control of locomotor activity and rearing.

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Year:  1985        PMID： 2858871     DOI： 10.1016/0091-3057(85)90401-0

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  28 in total

1.  Reinstatement of cocaine seeking in rats by the pharmacological stressors, corticotropin-releasing factor and yohimbine: role for D1/5 dopamine receptors.

Authors:  Z J Brown; D A Kupferschmidt; Suzanne Erb
Journal:  Psychopharmacology (Berl)       Date:  2012-06-17       Impact factor: 4.530

2.  Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice.

Authors:  Roberto Frau; Giuliano Pillolla; Valentina Bini; Simone Tambaro; Paola Devoto; Marco Bortolato
Journal:  Psychoneuroendocrinology       Date:  2012-08-09       Impact factor: 4.905

3.  Dopamine D-2 receptor agonist-induced behavioural depression: critical dependence upon postsynaptic dopamine D-1 function. A behavioural and biochemical study.

Authors:  D M Jackson; S B Ross; L G Larsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1989-10       Impact factor: 3.000

4.  Differential effects of dopamine D1 and D 2/3 receptor antagonism on motor responses.

Authors:  Steven Tran; Magda Nowicki; Arrujyan Muraleetharan; Robert Gerlai
Journal:  Psychopharmacology (Berl)       Date:  2014-08-20       Impact factor: 4.530

5.  The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations.

Authors:  Jennifer M Wright; May R S Dobosiewicz; Paul B S Clarke
Journal:  Psychopharmacology (Berl)       Date:  2012-09-28       Impact factor: 4.530

6.  Role of genotype and dopamine receptors in behaviour of inbred mice in a forced swimming test.

Authors:  E M Nikulina; J A Skrinskaya; N K Popova
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

7.  Biphasic locomotor effects of the dopamine D1 agonist SKF 38393 and their attenuation in non-habituated mice.

Authors:  E Tirelli; P Terry
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

8.  Vendor differences in alcohol consumption and the contribution of dopamine receptors to Pavlovian-conditioned alcohol-seeking in Long-Evans rats.

Authors:  Lindsay M Sparks; Joanna M Sciascia; Ziada Ayorech; Nadia Chaudhri
Journal:  Psychopharmacology (Berl)       Date:  2013-10-06       Impact factor: 4.530

9.  Altered striatal function in a mutant mouse lacking D1A dopamine receptors.

Authors:  J Drago; C R Gerfen; J E Lachowicz; H Steiner; T R Hollon; P E Love; G T Ooi; A Grinberg; E J Lee; S P Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

10.  Early and prolonged exposure to reward delay: effects on impulsive choice and alcohol self-administration in male rats.

Authors:  Jeffrey S Stein; Patrick S Johnson; C Renee Renda; Rochelle R Smits; Kennan J Liston; Timothy A Shahan; Gregory J Madden
Journal:  Exp Clin Psychopharmacol       Date:  2013-01-28       Impact factor: 3.157
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