Literature DB >> 28586701

The extent of and factors associated with self-reported overdose and self-reported receipt of naloxone among people who inject drugs (PWID) in England, Wales and Northern Ireland.

Charlotte O'Halloran1, Katelyn Cullen2, Jaquelyn Njoroge2, Lucy Jessop3, Josie Smith4, Vivian Hope2, Fortune Ncube2.   

Abstract

BACKGROUND: Overdose is a major cause of death among PWID, and for opioid overdoses naloxone administration can reduce harm. However, globally there is limited national level data on the extent of non-fatal overdose and naloxone uptake. The first national level data on the extent of self-reported overdose and self-reported receipt of naloxone among UK PWID, providing a baseline to monitor the impact of the recent policy change regarding naloxone availability, is presented.
METHODS: Data on self-reported overdose and receipt of naloxone during the preceding year for 2013-2014 from a national survey of PWID was analysed. Participants who reported injecting during the preceding year were included.
RESULTS: Participants (3850) were predominantly male (75%); mean age was 36 years. The most commonly injected drugs were: heroin (91%), crack (45%) and amphetamine (29%). 15% (591) reported overdosing during the preceding year. There were no differences in the proportion reporting overdose by age or gender, but overdose was more common among those who: injected multiple drugs; recently ceased addiction treatment; injected with used needles/syringes; ever had transactional sex; had used a sexual health clinic or emergency department and lived in Wales or Northern Ireland. Among those reporting an overdose during the preceding year, a third reported two to four overdoses and 7.5% five or more overdoses; half reported receiving naloxone. Those reporting naloxone receipt in the preceding year were more likely to: live in Wales or Northern Ireland; ever received used needles/syringes; ever been imprisoned; and less likely to have injected two drug types.
CONCLUSION: These data provide a baseline for monitoring the impact of the 2015 UK policy change to improve take-home naloxone access. Interventions tackling overdose should promote naloxone awareness and access, and target those who; are poly-drug injectors, have ceased treatment, share needles/syringes and whose drug use links to sexual activity. Crown
Copyright © 2017. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Harm reduction; Heroin; Naloxone; Overdose; People who inject drugs; United Kingdom

Mesh:

Substances:

Year:  2017        PMID: 28586701     DOI: 10.1016/j.drugpo.2017.05.017

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  5 in total

1.  Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings.

Authors:  Aurelia Collados-Ros; Carmen Torres-Sánchez; María Dolores Pérez-Cárceles; Aurelio Luna; Isabel Legaz
Journal:  Toxics       Date:  2022-06-11

2.  Explaining the Differences in Opioid Overdose Deaths between Scotland and England/Wales: Implications for European Opioid Policies.

Authors:  Jan van Amsterdam; Wim van den Brink; Mimi Pierce
Journal:  Eur Addict Res       Date:  2021-05-07       Impact factor: 3.015

3.  Increased risk of HIV and other drug-related harms associated with injecting in public places: national bio-behavioural survey of people who inject drugs.

Authors:  Kirsten M A Trayner; Andrew McAuley; Norah E Palmateer; David J Goldberg; Samantha J Shepherd; Rory N Gunson; Emily J Tweed; Saket Priyadarshi; Catriona Milosevic; Sharon J Hutchinson
Journal:  Int J Drug Policy       Date:  2020-01-22

4.  Evaluating the Link between BAFF System Gene Expression and Acute Rejection Development in Kidney Transplantation.

Authors:  Rafael Alfaro; Santiago Lorente; Víctor Jimenez-Coll; Helios Martínez-Banaclocha; José Antonio Galián; Carmen Botella; María Rosa Moya-Quiles; Manuel Muro-Pérez; Jesús de la Peña-Moral; Alfredo Minguela; Isabel Legaz; Manuel Muro
Journal:  J Clin Med       Date:  2022-07-07       Impact factor: 4.964

5.  A scoping review of factors that influence opioid overdose prevention for justice-involved populations.

Authors:  Christine E Grella; Erika Ostlie; Christy K Scott; Michael L Dennis; John Carnevale; Dennis P Watson
Journal:  Subst Abuse Treat Prev Policy       Date:  2021-02-22
  5 in total

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