Literature DB >> 2858552

Cocaine-like action of diphenhydramine in cat cerebral arteries.

G Balfagón, E J Marco.   

Abstract

Diphenhydramine (5.3 X 10(-7) M) significantly reduced the tritium efflux evoked by 10(-7) M tyramine from cat cerebral arteries preloaded with [3H]noradrenaline but not that brought about by 50 mM KCl. These results indicate the ability of diphenhydramine to block the amine neuronal uptake.

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Year:  1985        PMID: 2858552     DOI: 10.1111/j.2042-7158.1985.tb05027.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  1 in total

1.  Acceleration of rat brain beta-adrenoceptor subsensitivity following the coadministration of histamine receptor antagonists with imipramine.

Authors:  A A Alhaider; A A Mustafa
Journal:  Agents Actions       Date:  1989-11
  1 in total

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