Wided Kouidhi1, Letchumi Thannimalay2, Chen Sau Soon2, Mustafa Ali Mohd3. 1. University of Malaya, Kuala Lumpur, Malaysia (Department of Pharmacology Faculty of Medicine). wided.kouidhi@gmail.com. 2. SIRIM: Scientific and Industrial Research Institute of Malaysia, Selangor Darul Ehsan, Malaysia (Environment and Bioprocess Technology Centre). 3. University of Malaya, Kuala Lumpur, Malaysia (Department of Pharmacology Faculty of Medicine). mustafa@ummc.edu.my.
Abstract
OBJECTIVES: The purpose of this study has been to assess ambient bisphenol A (BPA) levels in workplaces and urine levels of workers and to establish a BPA database for different populations in Malaysia. MATERIAL AND METHODS: Urine samples were collected from plastic factory workers and from control subjects after their shift. Air samples were collected using gas analyzers from 5 sampling positions in the injection molding unit work area and from ambient air. The level of BPA in airborne and urine samples was quantified by the gas chromatography mass spectrometry - selected ion monitoring (GCMS-SIM) analysis. RESULTS: Bisphenol A was detected in the median range of 8-28.3 ng/m³ and 2.4-3.59 ng/m³ for the 5 sampling points in the plastic molding factory and in the ambient air respectively. The median urinary BPA concentration was significantly higher in the workers (3.81 ng/ml) than in control subjects (0.73 ng/ml). The urinary BPA concentration was significantly associated with airborne BPA levels (ρ = 0.55, p < 0.01). CONCLUSIONS: Our findings provide the first evidence that workers in a molding factory in Malaysia are occupationally exposed to BPA. Int J Occup Med Environ Health 2017;30(5):743-750. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
OBJECTIVES: The purpose of this study has been to assess ambient bisphenol A (BPA) levels in workplaces and urine levels of workers and to establish a BPA database for different populations in Malaysia. MATERIAL AND METHODS: Urine samples were collected from plastic factory workers and from control subjects after their shift. Air samples were collected using gas analyzers from 5 sampling positions in the injection molding unit work area and from ambient air. The level of BPA in airborne and urine samples was quantified by the gas chromatography mass spectrometry - selected ion monitoring (GCMS-SIM) analysis. RESULTS:Bisphenol A was detected in the median range of 8-28.3 ng/m³ and 2.4-3.59 ng/m³ for the 5 sampling points in the plastic molding factory and in the ambient air respectively. The median urinary BPA concentration was significantly higher in the workers (3.81 ng/ml) than in control subjects (0.73 ng/ml). The urinary BPA concentration was significantly associated with airborne BPA levels (ρ = 0.55, p < 0.01). CONCLUSIONS: Our findings provide the first evidence that workers in a molding factory in Malaysia are occupationally exposed to BPA. Int J Occup Med Environ Health 2017;30(5):743-750. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
Authors: Aleksandr B Stefaniak; Lauren N Bowers; Stephen B Martin; Duane R Hammond; Jason E Ham; J R Wells; Alyson R Fortner; Alycia K Knepp; Sonette du Preez; Jack R Pretty; Jennifer L Roberts; Johan L du Plessis; Austin Schmidt; Matthew G Duling; Andrew Bader; M Abbas Virji Journal: J Chem Health Saf Date: 2021-03-25
Authors: María Cecilia García-Espiñeira; Lesly Patricia Tejeda-Benítez; Jesus Olivero-Verbel Journal: Int J Environ Res Public Health Date: 2018-04-05 Impact factor: 3.390