Lindsey Rosman1, Elena Salmoirago-Blotcher2, John Cahill3, Karl L Wuensch4, Samuel F Sears5. 1. Department of Medicine, Yale School of Medicine, New Haven, CT, USA; Department of Psychology, East Carolina University, Greenville, NC, USA. 2. Department of Medicine, Brown University Medical School & The Miriam Hospital, Providence, RI, USA. 3. Department of Cardiovascular Sciences, East Carolina University, Greenville, NC, USA. 4. Department of Psychology, East Carolina University, Greenville, NC, USA. 5. Department of Psychology, East Carolina University, Greenville, NC, USA; Department of Cardiovascular Sciences, East Carolina University, Greenville, NC, USA.
Abstract
BACKGROUND: Depression and health behavior engagement are a critical issue for recovery and secondary prevention in heart failure patients. No prior studies have examined these important clinical outcomes in young women diagnosed with Peripartum Cardiomyopathy (PPCM). We sought to characterize the prevalence of depression and health behaviors in PPCM patients and examine whether depression is associated with reduced engagement in health behaviors. METHODS: A nation-wide, cohort of 177 PPCM patients (mean age of 34.8 ± 5.7 years; median time since diagnosis of 3.0 ± 4.3 years) from a web-based quality of life registry completed questionnaires about depression (Patient Health Questionnaire; a cutoff score ≥10 was used for depression screening) and health behaviors. T-tests, chi-square and linear regression were used to compare clinical characteristics and health behaviors among depressed and non-depressed women. RESULTS: The prevalence of clinical depression at enrollment was 32.3% and was associated with use of antihypertensive medications, disability insurance status, higher BMI, history of arrhythmia and current or past use of psychotropic medication. Health behavior engagement for diet, physical activity, and tobacco cessation were low in the overall sample and depressed PPCM patients were significantly less likely to attend medical appointments than non-depressed women. CONCLUSIONS: Nearly 1 in 3 PPCM survivors reported symptoms of clinical depression which was associated with worse attendance at medical follow-up visits. Further research is needed to develop risk stratification models and patient-centered interventions to improve clinical outcomes for PPCM survivors.
BACKGROUND:Depression and health behavior engagement are a critical issue for recovery and secondary prevention in heart failurepatients. No prior studies have examined these important clinical outcomes in young women diagnosed with Peripartum Cardiomyopathy (PPCM). We sought to characterize the prevalence of depression and health behaviors in PPCM patients and examine whether depression is associated with reduced engagement in health behaviors. METHODS: A nation-wide, cohort of 177 PPCM patients (mean age of 34.8 ± 5.7 years; median time since diagnosis of 3.0 ± 4.3 years) from a web-based quality of life registry completed questionnaires about depression (Patient Health Questionnaire; a cutoff score ≥10 was used for depression screening) and health behaviors. T-tests, chi-square and linear regression were used to compare clinical characteristics and health behaviors among depressed and non-depressedwomen. RESULTS: The prevalence of clinical depression at enrollment was 32.3% and was associated with use of antihypertensive medications, disability insurance status, higher BMI, history of arrhythmia and current or past use of psychotropic medication. Health behavior engagement for diet, physical activity, and tobacco cessation were low in the overall sample and depressed PPCM patients were significantly less likely to attend medical appointments than non-depressedwomen. CONCLUSIONS: Nearly 1 in 3 PPCM survivors reported symptoms of clinical depression which was associated with worse attendance at medical follow-up visits. Further research is needed to develop risk stratification models and patient-centered interventions to improve clinical outcomes for PPCM survivors.
Authors: Jakob Triebel; Maria Ludivina Robles-Osorio; Renata Garcia-Franco; Gonzalo Martínez de la Escalera; Carmen Clapp; Thomas Bertsch Journal: Front Endocrinol (Lausanne) Date: 2017-12-11 Impact factor: 5.555
Authors: Diana S Wolfe; Christina Liu; Jack Alboucai; Ariel Karten; Juliet Mushi; Shira Yellin; Julia L Berkowitz; Shayna Vega; Nicole Felix; Wasla Liaqat; Rohan Kankaria; Thammatat Vorawandthanachai; Anna E Bortnick Journal: J Cardiovasc Dev Dis Date: 2022-08-06
Authors: Eunjung Choi; Brigitte Kazzi; Bhavya Varma; Alexandra R Ortengren; Anum S Minhas; Arthur Jason Vaught; Wendy L Bennett; Jennifer Lewey; Erin D Michos Journal: Curr Cardiovasc Risk Rep Date: 2022-09-21